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HTR2A 抗体 (C-Term) (Fluoro594)

The 兔 多克隆 anti-HTR2A antibody is suitable to detect HTR2A in samples from 人 和 大鼠. It has been validated for FACS.
产品编号 ABIN7965059
发货至: 中国
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Quick Overview for HTR2A 抗体 (C-Term) (Fluoro594) (ABIN7965059)

抗原

See all HTR2A 抗体
HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))

适用

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人, 大鼠

宿主

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克隆类型

  • 99
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多克隆

标记

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This HTR2A antibody is conjugated to Fluoro594

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    C-Term

    原理

    Anti-5HT2A Receptor/HTR2A Antibody Fluoro594 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    different from the related mouse sequence by three amino acids,and from the related rat sequence by two amino acids.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human 5HT2A Receptor , different from the related mouse sequence by three amino acids, and from the related rat sequence by two amino acids.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))

    别名

    HTR2A

    背景

    Background: The mammalian HTR2A (5-HT2A receptor) is a subtype of the 5-HT2 receptor that belongs to the serotonin receptor family and is a G protein-coupled receptor (GPCR). This is the main excitatory receptor subtype among the GPCRs for serotonin (5-HT), although 5-HT2A may also have an inhibitory effect on certain areas such as the visual cortex and the orbit frontal cortex. This receptor was given importance first as the target of psychedelic drugs like LSD. Later it came back to prominence because it was also found to be mediating, at least partly, the action of many antipsychotic drugs, especially the atypical ones. 5-HT2A also happens to be a necessary receptor for the spread of the human polyoma virus called JC virus. Sparkes et al. (1991) concluded that the gene is located on 13q14-q21 in man and on chromosome 14 in the mouse.

    Gene Full Name: 5-hydroxytryptamine receptor 2A

    Sequence Similarities: Belongs to the G-protein coupled receptor 1 family.

    基因ID

    3356

    UniProt

    P28223

    途径

    JAK/STAT Signaling, Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process
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