PDPK1 抗体 (AA 114-436)
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北京 101111
Quick Overview for PDPK1 抗体 (AA 114-436) (ABIN7964987)
抗原
See all PDPK1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 114-436
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原理
- Anti-PDK1 Antibody
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交叉反应 （详细）
- No cross reactivity with other proteins.
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预测反应
- Human PDK1 shares 94.7%,95.7% amino acid (aa) sequence identity with mouse,rat PDK1,respectively.
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产品特性
- Anti-PDK1 Antibody. Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PDK1 recombinant protein (Position: Y114-A436). Human PDK1 shares 94.7% and 95.7% amino acid (aa) sequence identity with mouse and rat PDK1, respectively.
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亚型
- IgG
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anti-3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) (pSer241) antibody
PDPK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) (AA 150-429) antibodyPDPK1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) (AA 1-429) antibodyPDPK1 适用: 人 WB, PLA 宿主: 小鼠 Polyclonal unconjugated
anti-3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) (AA 457-556) antibodyPDPK1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 7E4G11 unconjugated
anti-3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) (AA 1-150) antibodyPDPK1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) antibodyPDPK1 适用: 人, 大鼠, 猴 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 4A11 unconjugated
anti-3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) (C-Term) antibodyPDPK1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) (AA 83-338) antibodyPDPK1 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) (AA 457-556) antibodyPDPK1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E2 unconjugated
anti-3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) antibodyKD Validated PDPK1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB5425 unconjugated Recombinant Antibody
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- PDPK1 (3-phosphoinositide Dependent Protein Kinase-1 (PDPK1))
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别名
- PDK1
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背景
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Background: Pyruvate dehydrogenase lipoamide kinase isozyme 1, mitochondrial is an enzyme that in humans is encoded by the PDK1 gene. Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene.
Gene Full Name: pyruvate dehydrogenase kinase 1
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分子量
- 46 kDa
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基因ID
- 5163
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UniProt
- Q15118
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途径
- PI3K-Akt Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Regulation of Cell Size, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
抗原
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