HAAO 抗体 (AA 52-286) (HRP)
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北京 101111
Quick Overview for HAAO 抗体 (AA 52-286) (HRP) (ABIN7964895)
抗原
See all HAAO 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 52-286
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原理
- Anti-HAAO Antibody HRP Conjugated
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交叉反应 （详细）
- No cross reactivity with other proteins.
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预测反应
- Human HAAO shares 86.3%,88.5% amino acid (aa) sequence identity with mouse,rat HAAO,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human HAAO recombinant protein (Position: E52-G286). Human HAAO shares 86.3% and 88.5% amino acid (aa) sequence identity with mouse and rat HAAO, respectively.
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亚型
- IgG
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anti-3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) (AA 97-196) antibody
HAAO 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4D1 unconjugated
anti-3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) (AA 153-223) antibodyHAAO 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) antibodyHAAO 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) (AA 101-200) antibodyHAAO 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) (AA 72-121) antibodyHAAO 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- HAAO (3-hydroxyanthranilate 3,4-Dioxygenase (HAAO))
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别名
- HAAO
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背景
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Background: 3-hydroxyanthranilate 3,4-dioxygenase (EC 1.13.11.6) is an enzyme encoded by the HAAO gene. 3-Hydroxyanthranilate 3,4-dioxygenase is a monomeric cytosolic protein belonging to the family of intramolecular dioxygenases containing nonheme ferrous iron. It is widely distributed in peripheral organs, such as liver and kidney, and is also present in low amounts in the central nervous system. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurologic and inflammatory disorders. HAAO has been suggested to play a role in disorders associated with altered tissue levels of QUIN.
Gene Full Name: 3-hydroxyanthranilate 3,4-dioxygenase
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基因ID
- 23498
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UniProt
- P46952
抗原
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