Recombinant YTHDF2 抗体
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北京 101111
Quick Overview for Recombinant YTHDF2 抗体 (ABIN7938551)
抗原
See all YTHDF2 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- YTHDF2 antibody (rAb), 100 μg (Clone 3L6)
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纯化方法
- Protein A Chromatography
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免疫原
- This antibody was raised against the YTHDF2 fusion protein.
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亚型
- IgG
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anti-YTH Domain Family, Member 2 (YTHDF2) (N-Term) antibody
YTHDF2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-YTH Domain Family, Member 2 (YTHDF2) (AA 201-500) antibodyYTHDF2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-YTH Domain Family, Member 2 (YTHDF2) (AA 1-579) antibodyYTHDF2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-YTH Domain Family, Member 2 (YTHDF2) (AA 300-350) antibodyYTHDF2 适用: 人, 小鼠 WB, FACS 宿主: 兔 Monoclonal BLR297M unconjugated Recombinant Antibody
anti-YTH Domain Family, Member 2 (YTHDF2) (AA 300-350) antibodyYTHDF2 适用: 人, 小鼠 WB, FACS 宿主: 兔 Monoclonal BLR297M unconjugated Recombinant Antibody
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应用备注
- WB: 1:5000-1:50000 dilution
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限制
- 仅限研究用
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缓冲液
- Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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- YTHDF2 (YTH Domain Family, Member 2 (YTHDF2))
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别名
- YTHDF2
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背景
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Background_Plain: YTHDF2 (YT521-B homology domain family 2, also known as CAHL, HGRG8, NY-REN-2) is a member of the YTH (YT521-B homology) superfamily containing YTH domain. Human YTH domain family proteins include three members, YTHDF1-3, which mainly localized in the cytoplasm. YTHDF proteins contain a highly conserved single-stranded RNA-binding domain which can specifically recognize and bind m6A-containing RNAs. An important role of YTHDF2 is in regulating mRNA stability. YTHDF2 recognizes many m6A-containing mRNAs that are not being actively translated and recruits them to cytoplasmic processing (P) bodies for degradation. YTHDF2 preserves 5'UTR methylation of stress- induced transcripts and promotes cap-independent mRNA translation by competitive binding and limiting the m6A 'eraser' FTO from demethylation.
Aliases: YTH N6-Methyladenosine RNA Binding Protein 2, HGRG8
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分子量
- 62 kDa
抗原
-
