电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

SMC3 抗体 (acLys105, acLys106, C-Term)

This 小鼠 单克隆 antibody specifically detects SMC3 in WB. It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN7938499
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for SMC3 抗体 (acLys105, acLys106, C-Term) (ABIN7938499)

抗原

See all SMC3 抗体
SMC3 (Structural Maintenance of Chromosomes 3 (SMC3))

适用

  • 77
  • 38
  • 31
  • 8
  • 7
  • 7
  • 7
  • 5
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
人, 小鼠

宿主

  • 71
  • 6
  • 1
小鼠

克隆类型

  • 53
  • 25
单克隆

标记

  • 40
  • 7
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SMC3 antibody is un-conjugated

应用范围

  • 49
  • 22
  • 17
  • 16
  • 14
  • 13
  • 12
  • 12
  • 10
  • 8
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 15
    • 10
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    acLys105, acLys106, C-Term

    原理

    SMC3 K105acK106ac antibody (mAb)

    纯化方法

    Protein G Chromatography

    免疫原

    This SMC3 antibody was raised against a peptide in the C-terminal region of human SMC3.

    亚型

    IgG1
  • 应用备注

    WB*: 1:500 - 1:1,000 dilution The addition of 0.05 % Tween 20 in the blocking buffer and primary antibody incubation buffer is recommended to aid in detection by Western blot. Individual optimization may be required.

    限制

    仅限研究用
  • 缓冲液

    Purified IgG in PBS, 30 % glycerol, 0.035 % Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

    储存条件

    -20 °C

    储存方法

    Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

    有效期

    24 months
  • 抗原

    SMC3 (Structural Maintenance of Chromosomes 3 (SMC3))

    别名

    SMC3

    背景

    Background_Plain: The Structural Maintenance of Chromosomes (SMC) family proteins play critical roles in various nuclear events that require structural changes of chromosomes, including mitotic chromosome organization, DNA recombination and repair and global transcriptional repression.SMC3 is a component of the cohesin complex that plays an essential role during chromatid segregation. SMC3 is also involved in DNA recombination and repair, mitotic chromosome organization and microtubule-mediated intracellular transport. SMC3 is acetylated during replication, which is essential for cohesion, and is phosphorylated by ATM after DNA double strand breakage. This antibody is acetylated at lysine 105/106.SMC3 is frequently elevated in human colon carcinoma and overexpression of the protein transforms fibroblasts.

    Aliases: BAM, BMH, HCAP, CDLS3, CSPG6, SMC3L1

    分子量

    141 kDa

    NCBI登录号

    NP_005436

    途径

    Stem Cell Maintenance
You are here: