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Recombinant SIRT3 抗体

The 兔 单克隆 anti-SIRT3 antibody (Clone 2P6) (ABIN7938489) specifically detects SIRT3 in WB. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7938489
发货至: 中国
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中国
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Quick Overview for Recombinant SIRT3 抗体 (ABIN7938489)

抗原

See all SIRT3 抗体
SIRT3 (Sirtuin 3 (SIRT3))

抗体类型

Recombinant Antibody

适用

  • 105
  • 45
  • 23
  • 9
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 89
  • 23
  • 2
  • 2
  • 1

克隆类型

  • 86
  • 32
单克隆

标记

  • 70
  • 14
  • 10
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
This SIRT3 antibody is un-conjugated

应用范围

  • 104
  • 56
  • 51
  • 13
  • 12
  • 10
  • 9
  • 9
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB)

克隆位点

2P6
  • 原理

    SIRT3 antibody (rAb), 100 μl (Clone 2P6)

    纯化方法

    Protein A Chromatography

    免疫原

    This antibody was raised against the SIRT3 fusion protein.

    亚型

    IgG
  • 应用备注

    WB: 1:5000-1:150000 dilution

    限制

    仅限研究用
  • 缓冲液

    Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

    储存条件

    -20 °C

    储存方法

    Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

    有效期

    24 months
  • 抗原

    SIRT3 (Sirtuin 3 (SIRT3))

    别名

    SIRT3

    背景

    Background_Plain: Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) and SIRT3 is the only sirtuin whose increased expression has been shown to correlate with an extended life span in humans. It is localized in the mitochondrial matrix, where it regulates the acetylation levels of metabolic enzymes, including acetyl coenzyme A synthetase 2. SIRT3 is stress-responsive, and its increased expression protects myocytes from genotoxic and oxidative stress-mediated cell death. full-length hSIRT3 (44 kDa) is an inert protein and that it is activated inside the mitochondria following deletion of 142 amino acids of the N-terminal segment. This processed form of SIRT3 is approximately 28 kDa and possesses deacetylase activity. The full SIRT3 is a 44 kDa protein and is processed by mitochondrial processing peptidase (MPP) to give a 28 kDa product.

    Aliases: SIRT-3, Sirtuin 3, Sir1-Like 3, EC 3.5.1

    分子量

    44 kDa
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