Recombinant SIRT3 抗体
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Quick Overview for Recombinant SIRT3 抗体 (ABIN7938489)
抗原
See all SIRT3 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- SIRT3 antibody (rAb), 100 μl (Clone 2P6)
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纯化方法
- Protein A Chromatography
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免疫原
- This antibody was raised against the SIRT3 fusion protein.
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亚型
- IgG
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应用备注
- WB: 1:5000-1:150000 dilution
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限制
- 仅限研究用
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缓冲液
- Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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- SIRT3 (Sirtuin 3 (SIRT3))
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别名
- SIRT3
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背景
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Background_Plain: Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) and SIRT3 is the only sirtuin whose increased expression has been shown to correlate with an extended life span in humans. It is localized in the mitochondrial matrix, where it regulates the acetylation levels of metabolic enzymes, including acetyl coenzyme A synthetase 2. SIRT3 is stress-responsive, and its increased expression protects myocytes from genotoxic and oxidative stress-mediated cell death. full-length hSIRT3 (44 kDa) is an inert protein and that it is activated inside the mitochondria following deletion of 142 amino acids of the N-terminal segment. This processed form of SIRT3 is approximately 28 kDa and possesses deacetylase activity. The full SIRT3 is a 44 kDa protein and is processed by mitochondrial processing peptidase (MPP) to give a 28 kDa product.
Aliases: SIRT-3, Sirtuin 3, Sir1-Like 3, EC 3.5.1
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分子量
- 44 kDa
抗原
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