PHF6 抗体 (N-Term)
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Quick Overview for PHF6 抗体 (N-Term) (ABIN7938407)
抗原
See all PHF6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- PHF6 antibody (pAb)
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纯化方法
- Affinity Purified
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免疫原
- This antibody was generated using a peptide from the N-terminal region of human PHF6 (PHD finger protein 6 isoform 1).
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亚型
- IgG
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应用备注
- WB*: 1:500 - 1:1,000 dilution *Note: Many chromatin-bound proteins are not soluble in a low salt nuclear extract and fractionate to the pellet. Therefore, we recommend a High Salt / Sonication Protocol when preparing nuclear extracts for Western blot.
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限制
- 仅限研究用
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缓冲液
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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- PHF6 (PHD Finger Protein 6 (PHF6))
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别名
- PHF6
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背景
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Background_Plain: PHF6 is a member of the plant homeodomain finger (PHF) family, which has a potential rode in regulation of chromatin accessibility to lineage-specific transcription factors as part of the nucleosome remodeling and deacetylase (NuRD) epigenetic complex. PHF6 has been reported as a tumor suppressor in association with hematopoietic malignancies including T-cell acute lymphoblastic leukemia (T-ALL) and acute myeloid leukemia (AML). PHF6 may have tissue-specific expression, and is overexpressed in both breast and colorectal cancers. Germline mutations in PHF6 are the cause of the Börjeson-Forssman-Lehmann X-linked intellectual disability syndrome (BFLS).
Aliases: PHD Finger Protein 6, CENP-31
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分子量
- 45 kDa
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NCBI登录号
- NP_115834
抗原
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