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NSUN2 抗体

This 兔 多克隆 antibody specifically detects NSUN2 in WB. It exhibits reactivity toward 人.
产品编号 ABIN7938379
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for NSUN2 抗体 (ABIN7938379)

抗原

See all NSUN2 抗体
NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))

适用

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宿主

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克隆类型

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  • 2
多克隆

标记

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This NSUN2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 原理

    NSUN2 antibody (pAb)

    纯化方法

    Protein A Chromatography

    免疫原

    Peptide within the human NSUN2 (RNA cytosine C(5)-methyltransferase NSUN2) isoform 1.

    亚型

    IgG
  • 应用备注

    WB: 0.5 - 2.0 μg/mL dilution

    限制

    仅限研究用
  • 缓冲液

    Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

    储存条件

    -20 °C

    储存方法

    Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

    有效期

    24 months
  • 抗原

    NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))

    别名

    NSUN2

    背景

    Background_Plain: NSUN2 (NOP2/Sun Domain Family, Member 2), also called TRM4 (TRNA Methyltransferase 4 Homolog), is a member of NSUN family. It's a RNA methyltransferase that methylates tRNAs, and possibly RNA polymerase III transcripts. NSUN2 also methylates cytosine to 5-methylcytosine (m5C) at positions 34 and 48 of intron containing. tRNA(Leu)(CAA) precursors, and at positions 48, 49 and 50 of tRNA(Gly)(GCC) precursors. It may act downstream of Myc to regulate epidermal cell growth and proliferation.NSUN2 is required for proper spindle assembly and chromosome segregation, independently of its methyltransferase activity.

    Aliases: NOP2/Sun RNA Methyltransferase Family Member 2, Myc-Induced SUN-Domain-Containing Protein, MISU, SAKI, MRT5

    分子量

    100 kDa

    NCBI登录号

    NP_060225
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