METTL16 抗体
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北京 101111
Quick Overview for METTL16 抗体 (ABIN7938345)
抗原
See all METTL16 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- METTL16 antibody (pAb)
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纯化方法
- Protein A Chromatography
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免疫原
- This METTL16 antibody was raised against a fusion protein corresponding to human METTL16.
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亚型
- IgG
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应用备注
- WB: 0.5 μg/mL-2 μg/mL For optimal results, primary antibody incubations should be performed at room temperature. The addition of 0.05 % Tween 20 to all blocking solutions may also reduce background. Individual optimization may be required.
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限制
- 仅限研究用
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缓冲液
- PBS containing 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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- METTL16 (Methyltransferase Like 16 (METTL16))
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别名
- METTL16
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背景
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Background_Plain: N6-methylated adenine (m6A) is prevalently present in nearly all RNA types and can be found in all organisms from bacteria to humans. It preferentially appears around stop codons and within long internal exons in mammalian messager RNAs. m6A plays an important role in the efficiency of mRNA splicing, processing, translation efficiency, editing and mRNA stability. m6A also occurs in other RNA molecules, such as primary miRNA (pri-miRNAs). METTL16 (Methyltransferase-Like Protein 16) is an RNA N6-methyltransferase that methylates adenosine residues of a subset of mRNAs and U6 smaller nuclear RNAs. METTL16 controls a significant portion of m6A epitranscriptome by regulating SAM homeostasis and plays a role in S-adenosyl-L-methionine homeostasis by regulating the expression of MAT2A transcripts.
Aliases: Methyltransferase-Like Protein 16
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分子量
- 64.9 kDa
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NCBI登录号
- NP_076991
抗原
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