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METTL14 抗体

This 兔 多克隆 antibody specifically detects METTL14 in WB 和 IP. It exhibits reactivity toward 人.
产品编号 ABIN7938342
发货至: 中国
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Quick Overview for METTL14 抗体 (ABIN7938342)

抗原

See all METTL14 抗体
METTL14 (Methyltransferase Like 14 (METTL14))

适用

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宿主

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克隆类型

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多克隆

标记

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This METTL14 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP)
  • 原理

    METTL14 antibody (pAb)

    纯化方法

    Affinity Purified

    免疫原

    This antibody was raised against a human peptide containing methyltransferase 14.

    亚型

    IgG
  • 应用备注

    WB: 1:500 - 1:2000 dilution IP: 4 µL per IP

    限制

    仅限研究用
  • 缓冲液

    Purified in PBS with 30 % glycerol and 0.035 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

    储存条件

    -20 °C

    储存方法

    Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

    有效期

    24 months
  • 抗原

    METTL14 (Methyltransferase Like 14 (METTL14))

    别名

    METTL14

    背景

    Background_Plain: N6-methylated adenine (m6A) is prevalently present in nearly all RNA types and can be found in all organisms from bacteria to humans. It preferentially appears around stop codons and within long internal exons in mammalian messager RNAs. m6A plays an important role in the efficiency of mRNA splicing, processing, translation efficiency, editing and mRNA stability. m6A also takes place in other RNA molecules, such as primary miRNA (pri-miRNAs). METTL14 (methyltransferase-like 14)forms a stable N6-methyltransferase heterodimer complex with METTL3, which catalyzes the generation of m6A modification on mammalian nuclear RNAs. METTL3 is the catalytically active subunit, while METTL14 plays a structural role critical for substrate recognition.

    Aliases: Methyltransferase Like 14, EC 2.1.1.62, N6-methyltransferase

    分子量

    55kDa

    NCBI登录号

    NP_066012
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