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KDM2B 抗体

The 小鼠 单克隆 anti-KDM2B antibody is suitable to detect KDM2B in samples from 人 和 小鼠. It has been validated for WB.
产品编号 ABIN7938318
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for KDM2B 抗体 (ABIN7938318)

抗原

See all KDM2B 抗体
KDM2B (Lysine (K)-Specific Demethylase 2B (KDM2B))

适用

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人, 小鼠

宿主

  • 38
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  • 1
小鼠

克隆类型

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单克隆

标记

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This KDM2B antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

K2K842-13
  • 原理

    KDM2B antibody (mAb) (Clone K2K842-13)

    纯化方法

    Protein A Chromatography

    免疫原

    This KDM2B antibody was raised against a peptide containing human lysine-specific demethylase 2B of isoform a.

    亚型

    IgG
  • 应用备注

    WB: 0.5 - 2 μg/mL dilution

    限制

    仅限研究用
  • 缓冲液

    Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

    储存条件

    -20 °C

    储存方法

    Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

    有效期

    24 months
  • 抗原

    KDM2B (Lysine (K)-Specific Demethylase 2B (KDM2B))

    别名

    KDM2B

    背景

    Background_Plain: KDM2B (lysine (K)-specific demethylase 2B), also known as FBXL10 (F-box and leucine-rich repeat protein 10) is a histone demethylase that preferentially demethylates trimethylated lysine 4 (K4me3) and dimethylated lysine 36 (K36me2) of histone H3. KDM2B displays weak or no activity for mono- and trimethylated H3K36. KDM2B preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which results in inhibition of cell growth and proliferation. KDM2B may also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

    Aliases: FBXL10

    分子量

    100 kDa

    NCBI登录号

    NP_115979

    途径

    Tube Formation, Warburg Effect
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