KDM2B 抗体
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北京 101111
Quick Overview for KDM2B 抗体 (ABIN7938317)
抗原
See all KDM2B 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- KDM2B antibody (mAb) (Clone K2K842-13)
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纯化方法
- Protein A Chromatography
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免疫原
- This KDM2B antibody was raised against a peptide containing human lysine-specific demethylase 2B of isoform a.
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亚型
- IgG
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应用备注
- WB: 0.5 - 2 μg/mL dilution
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限制
- 仅限研究用
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缓冲液
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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- KDM2B (Lysine (K)-Specific Demethylase 2B (KDM2B))
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别名
- KDM2B
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背景
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Background_Plain: KDM2B (lysine (K)-specific demethylase 2B), also known as FBXL10 (F-box and leucine-rich repeat protein 10) is a histone demethylase that preferentially demethylates trimethylated lysine 4 (K4me3) and dimethylated lysine 36 (K36me2) of histone H3. KDM2B displays weak or no activity for mono- and trimethylated H3K36. KDM2B preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which results in inhibition of cell growth and proliferation. KDM2B may also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
Aliases: FBXL10
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分子量
- 100 kDa
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NCBI登录号
- NP_115979
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途径
- Tube Formation, Warburg Effect
抗原
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