KDM5B 抗体
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北京 101111
Quick Overview for KDM5B 抗体 (ABIN7938293)
抗原
See all KDM5B 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- JARID1B / KDM5B antibody (pAb)
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纯化方法
- Protein A Chromatography
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免疫原
- This antibody was raised against a human peptide belonging to demethyase JARID1B.
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亚型
- IgG
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anti-Lysine (K)-Specific Demethylase 5B (KDM5B) (AA 231-319) antibody
KDM5B 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1G10 unconjugated
anti-Lysine (K)-Specific Demethylase 5B (KDM5B) (AA 231-319) antibodyKDM5B 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 7H3D7 unconjugated
anti-Lysine (K)-Specific Demethylase 5B (KDM5B) (AA 65-165) antibodyKDM5B 适用: 人, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 5B (KDM5B) (AA 231-319) antibodyKDM5B 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 5B (KDM5B) (AA 1494-1544) antibodyKDM5B 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 5B (KDM5B) (AA 784-883) antibodyKDM5B 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 5B (KDM5B) (AA 1494-1544) antibodyKDM5B 适用: 人 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 5B (KDM5B) (AA 641-685), (Middle Region) antibodyKDM5B 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 5B (KDM5B) antibodyKDM5B 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 5B (KDM5B) (AA 231-319) antibodyKDM5B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4F12 unconjugated
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应用备注
- ChIP-Seq: 10 µL each
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限制
- 仅限研究用
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缓冲液
- Purified IgG in PBS, 30 % glycerol, 0.035 % Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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- KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))
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别名
- JARID1B
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背景
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Background_Plain: Lysine (K)-specific demethylase 5B (KDM5B), also known as Jumonji, AT rich interactive domain 1B (JARID1B), is a histone demethylase that specifically demethylates lysine 4 of histone H3 (H3K4), thereby playing a central role in defining the histone code. KDM5B demethylates trimethylated, dimethylated and monomethylated H3K4. It does not demethylate histone H3K9 or H3K27. KDM5B functions as a transcriptional corepressor for FOXG1B and PAX9. KDM5B induces the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, it may act as a tumor suppressor for melanoma.
Aliases: Lysine Demethylase 5B, lysine (K)-specific demethylase 5B
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分子量
- 180 kDa
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NCBI登录号
- NP_006609
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途径
- Warburg Effect
抗原
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