ING5 抗体
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北京 101111
Quick Overview for ING5 抗体 (ABIN7938284)
抗原
See all ING5 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- ING5 antibody (mAb) (Clone 7A11)
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纯化方法
- Protein G Chromatography
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免疫原
- This antibody was raised against full length recombinant human ING5 (Inhibitor of growth protein 5) protein.
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亚型
- IgG2a
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anti-Inhibitor of Growth Family, Member 5 (ING5) (AA 1-240) antibody
ING5 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 5 (ING5) (AA 127-140) antibodyING5 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 5 (ING5) (AA 1-220) antibodyING5 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 5 (ING5) (AA 24-84) antibodyING5 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 5 (ING5) (AA 32-207) antibodyING5 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 5 (ING5) (AA 35-84) antibodyING5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 5 (ING5) antibodyING5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 5 (ING5) (AA 91-119) antibodyING5 适用: 人 WB 宿主: 兔 Polyclonal RB23813 unconjugated
anti-Inhibitor of Growth Family, Member 5 (ING5) (AA 125-150) antibodyING5 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 5 (ING5) antibodyING5 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 0.5 - 2 μg/mL IP: 5 μg/mL This antibody is also available as an AbFlex engineered recombinant antibody. For details on the corresponding AbFlex Recombinant Antibody, see Catalog No. 91329.
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限制
- 仅限研究用
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缓冲液
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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- ING5 (Inhibitor of Growth Family, Member 5 (ING5))
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别名
- ING5
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背景
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Background_Plain: ING5 (Inhibitor of Growth 5) possesses different structural and functional elements, including a PHD (plant homeodomain), an NCR (novel conserved region), a LZL (leucine zipper like) finger, and two NLS (nuclear localization sequence) motifs. ING proteins bind to methylated core histones through their PHD motif, notably ING5 reads histone H3 when di- or trimethylated at lysine 4 (H3K4me2/3). ING5 is a subunit of two distinct histone acetyltransferase (HAT) complexes with HBO1 or MOZ/MORF as the two catalytic subunits. These complexes contain two different alternative scaffolding proteins, i.e. a BRPF protein or a JADE protein, that determine their specificity towards different core histones. ING complexes appear to participate in transcription, for example by interacting with transcriptional regulators such as the tumor suppressor p53 and through the ability of ING5 to recognize H3K4me3, a mark associated with open chromatin and transcribed genes.
Aliases: Inhibitor of growth protein 5, p28ING5
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分子量
- 30 kDa
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NCBI登录号
- NP_001317091
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途径
- Chromatin Binding
抗原
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