Recombinant CBX5 抗体
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北京 101111
Quick Overview for Recombinant CBX5 抗体 (ABIN7938268)
抗原
See all CBX5 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- HP1 antibody (rAb), 100 μg (Clone 240145F11)
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纯化方法
- Protein A Chromatography
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免疫原
- This antibody was raised against the HP1 fusion protein.
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亚型
- IgG
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应用备注
- WB: 1:5000-1:50000 dilution
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限制
- 仅限研究用
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缓冲液
- Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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- CBX5 (Chromobox Homolog 5 (CBX5))
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别名
- HP1
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背景
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Background_Plain: HP1 (Heterochromatin protein 1) is a chromosomal protein that participates in both chromatin packaging and gene silencing. Three HP1 isoforms (a, b and g) occur in mammals. The chromodomain (Chromatin Organization Modifier) of HP1a is responsible for binding to Histone H3 methyl Lys9, although additional factors are required to specify the HP1 targeting. The chromoshadow domain mediates interactions with a number of nuclear proteins, including SuvH39 (a Histone H3 Lysine methyltransferase), the DNA methyltransferases DNMT1 and DNMT3A or the large subunit of the chromatin assembly factor-1 (CAF-1). Dysfunction of HP1a plays a critical role in tumorigenesis, and is implicated in the invasive/metastatic phenotype of breast cancer.
Aliases: CBX5, HP1, Hp1a
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分子量
- 22 kDa
抗原
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