HNRNPC 抗体
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北京 101111
Quick Overview for HNRNPC 抗体 (ABIN7938263)
抗原
See all HNRNPC 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- HNRNPC antibody (pAb)
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纯化方法
- Protein A Chromatography
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免疫原
- Peptide containing a sequence fragment corresponding to human heterogeneous nuclear ribonucleoprotein C.
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亚型
- IgG
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anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) antibody
KO Validated HNRNPC 适用: 人 WB, IF, IHC (p), ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) antibodyHNRNPC 适用: 人 WB, IHC, ELISA, IF, IP, FACS 宿主: 兔 Monoclonal 9G1 unconjugated Recombinant Antibody
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (pSer260) antibodyHNRNPC 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (C-Term) antibodyHNRNPC 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (AA 1-250) antibodyHNRNPC 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E8 unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) antibodyHNRNPC 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 23GB6125 unconjugated Recombinant Antibody
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (C-Term) antibodyHNRNPC 适用: 人, 兔, Cow, 犬, Pig, 马, 猴, 山羊, 豚鼠, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (AA 279-306), (C-Term) antibodyHNRNPC 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB24645 unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (AA 241-290) antibodyHNRNPC 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (AA 1-142), (N-Term) antibodyHNRNPC 适用: 人, 大鼠, 小鼠, 兔, Cow WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 0.5 - 2 μg/mL For optimal results, primary antibody incubations should be performed at room temperature. The addition of 0.05 % Tween 20 to all blocking solutions may also reduce background. Individual optimization may be required.
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限制
- 仅限研究用
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缓冲液
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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- HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))
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别名
- HNRNPC
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背景
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Background_Plain: HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C) is a member of the subfamily nuclear ribonucleoproteins (hnRNPs) involved in pre-mRNA processing, mRNA metabolism, and transport. These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene (C1 and C2). HNRNPC is a critical alternative splicing regulator that complexes with heterogeneous nuclear RNA (hnRNA) and plays an essential role in RNA maturation, stabilization, translocation, and posttranscriptional modification. Cellular homeostasis, among other cellular processes, is regulated by RNA alternative splicing. Alternative splicing disfunction contributes to many disorders, including cancer. The up regulation of HNRNPC expression has been tied to cancer progression and is thought to function by regulating RNA splicing, RNA expression, RNA stability, mRNA translation, m6A RNA methylation, and dsRNA induced interferon response.
Aliases: Heterogeneous Nuclear Ribonucleoprotein C, hnRNP C, HNRPC
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分子量
- 37 kDa
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UniProt
- P07910
抗原
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