HIRA 抗体
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北京 101111
Quick Overview for HIRA 抗体 (ABIN7938156)
抗原
See all HIRA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- HIRA antibody (mAb) (Clone WC119.2H11)
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纯化方法
- Protein G Chromatography
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免疫原
- This HIRA antibody was raised against a GST-fusion protein containing residues 421-729 of human HIRA.
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亚型
- IgG
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应用备注
- WB: 1 - 2 μg/mL dilution For optimal results, we recommend the addition of 0.05 % Tween-20 to all blocking solutions to reduce background in Western blot.
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限制
- 仅限研究用
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缓冲液
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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- HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))
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别名
- HIRA
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背景
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Background_Plain: HIRA (DGCR1, TUP1) is a histone chaperone that preferentially places the variant Histone H3.3 in nucleosomes, replacing canonical Histone H3 during the cell cycle. HIRA is required for the periodic repression of histone gene transcription during the cell cycle and when complexed with ASF1a is involved in the formation of the senescence-associated heterochromatin foci.
Aliases: TUP1, DGCR1, TUPLE1
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分子量
- 120 kDa
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NCBI登录号
- NP_003316
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途径
- Chromatin Binding
抗原
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