Recombinant HDAC3 抗体
Our Local Distributor
北京 101111
Quick Overview for Recombinant HDAC3 抗体 (ABIN7938149)
抗原
See all HDAC3 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- HDAC3 antibody (rAb), 100 μg (Clone 2N1)
-
纯化方法
- Protein A Chromatography
-
免疫原
- This antibody was raised against the HDAC3 fusion protein.
-
亚型
- IgG
-
-
-
-
应用备注
- WB: 1:5000-1:50000 dilution IHC: 1:50-1:500 dilution
-
限制
- 仅限研究用
-
-
-
缓冲液
- Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
-
储存条件
- -20 °C
-
储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
-
有效期
- 24 months
-
-
- HDAC3 (Histone Deacetylase 3 (HDAC3))
-
别名
- HDAC3
-
背景
-
Background_Plain: Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. Histone deacetylase (HDAC) and histone acetyltransferase (HAT) are enzymes that regulate transcription by selectively deacetylating or acetylating the (amino groups of lysine's located near the amino termini of core histone proteins. At least 4 classes of HDAC were identified. HDAC3 is a class I HDAC. HDAC3 has histone deacetylase activity and may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. HDAC3 can also down-regulate p53 function and thus modulate cell growth and apoptosis. The gene encoding HDAC3 is regarded as a potential tumor suppressor gene.
Aliases: HD3, RPD3, RPD3-2
-
分子量
- 49 kDa
-
途径
- Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
-