DPPA4 抗体
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北京 101111
Quick Overview for DPPA4 抗体 (ABIN7938111)
抗原
See all DPPA4 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- DPPA4 antibody (pAb)
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纯化方法
- Protein A Chromatography
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免疫原
- This antibody was raised against a peptide corresponding to DPPA4.
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亚型
- IgG
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应用备注
- WB: 0.5 μg/mL-2 μg/mL
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限制
- 仅限研究用
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缓冲液
- PBS containing 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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- DPPA4 (Developmental Pluripotency Associated 4 (DPPA4))
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别名
- DPPA4
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背景
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Background_Plain: DPPA2 and DPPA4 (developmental pluripotency associated 2 and 4) are small heterodimerizing nuclear proteins linked in the biological processes of transcription and transcription regulation. The encoded proteins have a scaffold-attachment factor A/B, acinus and PIAS (SAP) domain that binds DNA and is thought to modify chromatin. The nuclear factor encoded by the gene is involved in the maintenance of pluripotency in stem cells and is found to be essential for embryogenesis. DPPA2 and DPPA4 are required to maintain H3K4me3 and H3K27me3 at important bivalent promoters depicted in pluripotent cells by low H3K4me3 levels and initiating but not elongating RNA polymerase II. This gene is thought to play an important role in tumor progression because when mutated it is highly expressed in embryonal carcinomas, pluripotent germ cell tumors, and other cancers.
Aliases: Developmental Pluripotency Associated 4
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分子量
- 42 kDa
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NCBI登录号
- NP_001335858
抗原
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