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DPPA4 抗体

This 兔 多克隆 antibody specifically detects DPPA4 in WB. It exhibits reactivity toward 人.
产品编号 ABIN7938109
发货至: 中国
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Quick Overview for DPPA4 抗体 (ABIN7938109)

抗原

See all DPPA4 抗体
DPPA4 (Developmental Pluripotency Associated 4 (DPPA4))

适用

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宿主

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克隆类型

  • 57
  • 4
多克隆

标记

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This DPPA4 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 原理

    DPPA4 antibody (pAb)

    纯化方法

    Protein A Chromatography

    免疫原

    This antibody was raised against a peptide corresponding to DPPA4.

    亚型

    IgG
  • 应用备注

    WB: 0.5 μg/mL-2 μg/mL

    限制

    仅限研究用
  • 缓冲液

    PBS containing 30 % glycerol and 0.035 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

    储存条件

    -20 °C

    储存方法

    Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

    有效期

    24 months
  • 抗原

    DPPA4 (Developmental Pluripotency Associated 4 (DPPA4))

    别名

    DPPA4

    背景

    Background_Plain: DPPA2 and DPPA4 (developmental pluripotency associated 2 and 4) are small heterodimerizing nuclear proteins linked in the biological processes of transcription and transcription regulation. The encoded proteins have a scaffold-attachment factor A/B, acinus and PIAS (SAP) domain that binds DNA and is thought to modify chromatin. The nuclear factor encoded by the gene is involved in the maintenance of pluripotency in stem cells and is found to be essential for embryogenesis. DPPA2 and DPPA4 are required to maintain H3K4me3 and H3K27me3 at important bivalent promoters depicted in pluripotent cells by low H3K4me3 levels and initiating but not elongating RNA polymerase II. This gene is thought to play an important role in tumor progression because when mutated it is highly expressed in embryonal carcinomas, pluripotent germ cell tumors, and other cancers.

    Aliases: Developmental Pluripotency Associated 4

    分子量

    42 kDa

    NCBI登录号

    NP_001335858
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