BRD7 抗体 (C-Term)
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Quick Overview for BRD7 抗体 (C-Term) (ABIN7938068)
抗原
See all BRD7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- BRD7 antibody (pAb)
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纯化方法
- Affinity Purified
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免疫原
- This BRD7 antibody was raised against a peptide within the C-terminal region of human BRD7.
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亚型
- IgG
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anti-Bromodomain Containing 7 (BRD7) (Internal Region) antibody
BRD7 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Containing 7 (BRD7) (AA 601-651) antibodyBRD7 适用: 人 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Containing 7 (BRD7) (AA 601-651) antibodyBRD7 适用: 人 WB, IHC, ICC, FACS, IP 宿主: 兔 Monoclonal BLR221K unconjugated Recombinant Antibody
anti-Bromodomain Containing 7 (BRD7) (AA 1-95) antibodyBRD7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Containing 7 (BRD7) (C-Term) antibodyBRD7 适用: 人, 大鼠, 犬, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Containing 7 (BRD7) (AA 387-418) antibodyBRD7 适用: 小鼠 WB 宿主: 兔 Polyclonal RB43270 unconjugated
anti-Bromodomain Containing 7 (BRD7) (AA 601-651) antibodyBRD7 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Containing 7 (BRD7) (AA 514-567) antibodyBRD7 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Containing 7 (BRD7) (AA 1-651) antibodyBRD7 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Bromodomain Containing 7 (BRD7) (AA 150-200) antibodyBRD7 适用: 人, 小鼠 WB, FACS 宿主: 兔 Monoclonal BLR220K unconjugated Recombinant Antibody
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应用备注
- WB*: 1:500 - 1:2,000 dilution For optimal results, primary antibody incubations should be performed at room temperature. The addition of 0.05 % Tween 20 to all blocking solutions may also reduce background. Individual optimization may be required. *Note: Many chromatin-bound proteins are not soluble in a low salt nuclear extract and fractionate to the pellet. Therefore, we recommend a High Salt / Sonication Protocol when preparing nuclear extracts for Western blot.
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限制
- 仅限研究用
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缓冲液
- Purified IgG in 70 mM Tris, 105 mM NaCl, 0.07 mM EDTA, 31 mM glycine, 0.035 % sodium azide, 30 % glycerol, 0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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- BRD7 (Bromodomain Containing 7 (BRD7))
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别名
- BRD7
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背景
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Background_Plain: BRD7 (Bromodomain-containing protein 7, aka CELTIX1) is a chromatin-associated protein component of both functional p53 and BRCA1 (breast cancer 1, early onset) pathways. BRD7 inhibit4ed cancer cell growth and metastasis and promotes apoptosis in vitro and in vivo via downregulating AKT pathway. BRD7 may also regulate signaling pathways like ras-raf-MEK-ERK and RB/E2F. Previous studies have also demonstrated that BRD7 was downregulated in huma breast cancer, and the downregulation is associated with tumor progression.
Aliases: Bromodomain containing 7, CELTIX1, BP75, SMARCI1
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分子量
- 75 kDa
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NCBI登录号
- NM_013263
抗原
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