BRD4 抗体 (C-Term)
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Quick Overview for BRD4 抗体 (C-Term) (ABIN7938066)
抗原
See all BRD4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- BRD4 antibody (pAb)
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纯化方法
- Protein A Chromatography
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免疫原
- This BRD4 antibody was raised against a peptide within the C-terminal region of human BRD4.
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亚型
- IgG
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应用备注
- *WB: 0.5 - 2.0 μg/mL dilution *For optimal results, primary antibody incubations should be performed at room temperature. The addition of 0.05 % Tween 20 to all blocking solutions may also reduce background. Individual optimization may be required.
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限制
- 仅限研究用
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缓冲液
- Purified rabbit IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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- BRD4 (Bromodomain Containing 4 (BRD4))
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别名
- BRD4
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背景
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Background_Plain: BRD4 (Bromodomain-containing protein 4, aka HUNK1) is a chromatin-associated protein with two bromo domains that binds acetylated histone H3 and H4. BRD4 is homologous to Xenopus MCAP, and like MCAP, BRD4 associates with chromosomes during mitosis, predominantly in the non-centromeric regions. A chromosomal aberration involving BRD4 (producing a BRD4-NUT fusion protein) is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. BRD4 is involved in the expression of extracellular matrix gene expression, and its misregulation may be involved in breast cancer progression.
Aliases: CAP, MCAP, HUNK1, HUNKI
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分子量
- 180 kDa
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NCBI登录号
- NP_490597
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途径
- Chromatin Binding, SARS-CoV-2 Protein Interactome
抗原
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