Recombinant BCL6 抗体
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北京 101111
Quick Overview for Recombinant BCL6 抗体 (ABIN7938057)
抗原
See all BCL6 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- BCL6 antibody (rAb), 100 μg (Clone 3K6)
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纯化方法
- Protein A Chromatography
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免疫原
- This antibody was raised against the BCL6 fusion protein.
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亚型
- IgG
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应用备注
- WB: 1:5000-1:50000 dilution
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限制
- 仅限研究用
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缓冲液
- Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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- BCL6 (B-Cell CLL/lymphoma 6 (BCL6))
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别名
- BCL6
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背景
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Background_Plain: BCL6, a zinc finger transcription factor, contains an N-terminal BTB/POZ domain and C-terminal zinc finger DNA-binding motifs and represses transcription of a wide range of target proteins and microRNAs. BCL6 protein has been reported as a master regulator of B lymphocyte development and growth and altered BCL6 protein expression was implicated in pathogenesis of diverse human hematologic malignancies, especially in the diffuse large B cell lymphoma (DLBCL). BCL6 is required for the development of T follicular helper T cells (TFH), a helper T cell subset required for the formation of mature and productive GCs. BCL6 has also been shown to play important regulatory roles in macrophages.
Aliases: B-Cell CLL/Lymphoma 6, BCL5, LAZ3, BCL6A, ZNF51, ZBTB27
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分子量
- 79 kDa
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途径
- Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
抗原
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