Topo IIalpha (pSer1106) 抗体 (Biotin)
Quick Overview for Topo IIalpha (pSer1106) 抗体 (Biotin) (ABIN746530)
抗原
适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- pSer1106
-
交叉反应
- 人, 斑马鱼
-
预测反应
- Dog,Sheep,Pig
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic phosphopeptide derived from human TOPO II Alpha around the phosphorylation site of Ser1106
-
亚型
- IgG
-
-
anti-Topo IIalpha (N-Term) antibody
适用: 人, 猴 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Topo IIalpha (pThr1343) antibody适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Topo IIalpha (pSer1525) antibody适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C for 12 months.
-
有效期
- 12 months
-
-
- Topo IIalpha
-
别名
- TOPO II Alpha
-
背景
-
Synonyms: DNA topoisomerasealpha, DNA topoisomerase 2-alpha, DNA topoisomerase II, alpha isozyme, TOP2, TP2A, TOP2A, DNA topoisomerase II 170 kD, DNA topoisomerase II alpha isozyme, DNA Topoisomerase2, TOP 2A, TopII alpha, Topo II alpha, Topoisomerase DNA II alpha 170 kDa, Topoisomerase II alpha 170 kDa, TOP2A_HUMAN.
Background: This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, alpha, is localized to chromsome 17 and the beta gene is localized to chromosome 3. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia.
-
基因ID
- 7153
抗原
-
