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CRTC2 抗体 (pSer171) (HRP)

This anti-CRTC2 antibody (ABIN745997) is a Rabbit Polyclonal antibody detecting CRTC2 in WB, ELISA. Suitable for Human, Mouse.
产品编号 ABIN745997
发货至: 中国

Quick Overview for CRTC2 抗体 (pSer171) (HRP) (ABIN745997)

抗原

See all CRTC2 抗体
CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))

适用

  • 64
  • 21
  • 7
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 56
  • 6
  • 4
  • 1

克隆类型

  • 58
  • 9
多克隆

标记

  • 32
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  • 2
  • 1
  • 1
  • 1
  • 1
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  • 1
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  • 1
  • 1
  • 1
  • 1
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This CRTC2 antibody is conjugated to HRP

应用范围

  • 53
  • 32
  • 17
  • 15
  • 7
  • 6
  • 5
  • 3
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 15
    • 8
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer171

    交叉反应

    人, 小鼠

    预测反应

    Rat,Dog,Pig

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human CREB regulated transcription coactivator 2 around the phosphorylation site of Ser171

    亚型

    IgG
  • 应用备注

    WB 1:300-5000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))

    别名

    TORC2

    背景

    Synonyms: TORC2, TORC-2, CREB-regulated transcription coactivator 2, Transducer of regulated cAMP response element-binding protein 2, Transducer of CREB protein 2, CRTC2

    Background: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. Regulates the expression of specific genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).

    基因ID

    200186

    UniProt

    Q53ET0

    途径

    AMPK Signaling, Carbohydrate Homeostasis
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