UTS2R 抗体 (2nd Cytoplasmic Loop)
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Quick Overview for UTS2R 抗体 (2nd Cytoplasmic Loop) (ABIN7885632)
抗原
See all UTS2R 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- 2nd Cytoplasmic Loop, AA 154-167
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原理
- A Rabbit Ployclonal Antibody to Urotensin II Receptor
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预测反应
- Bovine - identical, human,canine - 13,14 amino acid residues identical
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- (C)RPLDTVQRSKGYRK, corresponding to amino acid residues 154-167 of rat URIIR
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亚型
- IgG
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anti-Urotensin 2 Receptor (UTS2R) (N-Term) antibody
UTS2R 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Urotensin 2 Receptor (UTS2R) (C-Term) antibodyUTS2R 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Urotensin 2 Receptor (UTS2R) (AA 203-252) antibodyUTS2R 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 1:200
FC: The optimal concentration should be determined by the user
ICC: The optimal concentration should be determined by the user
IHC: The optimal concentration should be determined by the user
IP: The optimal concentration should be determined by the user
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说明
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Negative Control: (ABIN7237551)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 0.2 mL double distilled water (DDW)
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存液
- Without preservative
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- UTS2R (Urotensin 2 Receptor (UTS2R))
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别名
- Urotensin 2 receptor
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背景
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Synonyms: Urotensin 2 receptor, UR-II-R, UR2R, UTS2R, SENR, GPR14
Description: Urotensin II is a powerful vasoconstrictive substance. The human urotensin II receptor (UR-II-R) was originally isolated as an orphan receptor (GPR14) from neural and sensory tissues.1,2 Urotensin II is expressed in various human tissues such as the CNS, skeletal muscle, smooth muscle, pancreas, and heart.3-5 Binding of urotensin II to the receptor leads to activation of phospholipase C. The resulting increase in intracellular Ca2+ may cause the contraction of vascular smooth muscle. ERK1/2 phophorylation may also be involved in mediating the biological activities of urotensin II.6 Recently, evidence has accumulated indicating that urotensin II is also expressed in various kinds of tumor cells such as adrenal tumors and neuroblastomas. In those cells, urotensin II was reported to stimulate cell growth.7-9
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基因ID
- 57305
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UniProt
- P49684
抗原
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