TBXA2R 抗体 (3rd Intracellular Loop)
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Quick Overview for TBXA2R 抗体 (3rd Intracellular Loop) (ABIN7885574)
抗原
See all TBXA2R 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- 3rd Intracellular Loop, AA 225-239
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原理
- A Rabbit Polyclonal Antibody to Thromboxane A2 Receptor
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预测反应
- Rat - 14,15 amino acid residues identical, human - 12, mouse - 13
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- (C)HAREATQRPRD(S)EVE, corresponding to amino acid residues 225-239 of rat TBXA2R
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亚型
- IgG
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anti-Thromboxane A2 Receptor (TBXA2R) (AA 3-324) antibody
TBXA2R 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thromboxane A2 Receptor (TBXA2R) (AA 51-150) antibodyTBXA2R 适用: 人, 小鼠 ELISA, FACS, IF (cc), IF (p), ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Thromboxane A2 Receptor (TBXA2R) (C-Term) antibodyTBXA2R 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Thromboxane A2 Receptor (TBXA2R) (3rd Intracellular Loop), (AA 225-239) antibodyTBXA2R 适用: 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Thromboxane A2 Receptor (TBXA2R) (AA 13-27), (Extracellular), (N-Term) antibodyTBXA2R 适用: 人 WB, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-Thromboxane A2 Receptor (TBXA2R) (C-Term) antibodyVerified TBXA2R 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Thromboxane A2 Receptor (TBXA2R) (C-Term) antibodyTBXA2R 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Thromboxane A2 Receptor (TBXA2R) (Cytoplasmic Domain) antibodyTBXA2R 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Thromboxane A2 Receptor (TBXA2R) (AA 323-343) antibodyTBXA2R 适用: 人 WB, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thromboxane A2 Receptor (TBXA2R) antibodyTBXA2R 适用: 人 WB 宿主: 兔 Monoclonal 24GB1845 unconjugated Recombinant Antibody
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应用备注
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WB: 1:200
FC: The optimal concentration should be determined by the user
ICC: The optimal concentration should be determined by the user
IHC: 1:200
IP: The optimal concentration should be determined by the user
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说明
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Negative Control: (ABIN7237385)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 0.2 mL double distilled water (DDW)
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存液
- Without preservative
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- TBXA2R (Thromboxane A2 Receptor (TBXA2R))
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别名
- Prostanoid TP receptor
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背景
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Synonyms: Prostanoid TP receptor, TXA2-R, TBXA2R
Description: Thromboxane A2 (TxA2) is a prostanoid that is synthesized from arachidonic acid and plays an important role in haemostasis, a process regulating platelet aggregation and vascular tone. Thromboxane A2 binds to the thromboxane A2 receptor (TBXA2R) to induce strong vasoconstriction in renal arteries.Thromboxane A2 receptor is a seven-transmembrane G-protein coupled receptor localized on the cell membrane and in intracellular compartments. TBXA2R is expressed in the central nervous system in several types of cells, such as microglia, oligodendrocytes and astrocytes. Imbalances in the levels of the receptor is widely implicated in several cardiovascular, pulmonary, renal and prostate pathologies1-3.Thromboxane A2 receptor mediates vasoconstriction and ischemia and its activation is implicated in atherosclerosis and inflammation. Activation of the receptor induces endothelial cell apoptosis by inhibiting Akt phosphorylation and also inhibits endothelial cell migration and angiogenesis by decreasing Akt and eNOS phosphorylation1-3.
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基因ID
- 24816
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UniProt
- P34978
抗原
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