SYN2 抗体 (Domain G, Intracellular)
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Quick Overview for SYN2 抗体 (Domain G, Intracellular) (ABIN7885548)
抗原
See all SYN2 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 438-450, Domain G, Intracellular
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原理
- A Rabbit Polyclonal Antibody to Synapsin II
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预测反应
- Mouse - identical, human- 12,13 amino acid residues identical
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- (C)SGTLKEPDSSKTP, corresponding to amino acid residues 438-450 of rat Synapsin-2
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亚型
- IgG
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anti-Synapsin II (SYN2) (AA 497-582) antibody
SYN2 适用: 小鼠, 人, 大鼠, Pig WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Synapsin II (SYN2) antibodySYN2 适用: 小鼠, 人, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Synapsin II (SYN2) antibodyKO Validated SYN2 适用: 小鼠, 人, 大鼠 WB, IHC, IP, ICC, IHC (p) 宿主: 小鼠 Monoclonal 27E3 unconjugated
anti-Synapsin II (SYN2) antibodySYN2 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB4960 unconjugated Recombinant Antibody
anti-Synapsin II (SYN2) antibodySYN2 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB4660 unconjugated Recombinant Antibody
anti-Synapsin II (SYN2) (AA 88-422) antibodySYN2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Synapsin II (SYN2) antibodyKO Validated SYN2 适用: 小鼠, 人, 大鼠, Pig WB, IHC, IP, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Synapsin II (SYN2) (AA 348-448) antibodySYN2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Synapsin II (SYN2) (AA 438-450), (Domain G), (Intracellular) antibodySYN2 适用: 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 1:200
FC: The optimal concentration should be determined by the user
ICC: The optimal concentration should be determined by the user
IHC: 1:200
IP: The optimal concentration should be determined by the user
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说明
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Negative Control: (ABIN7237311)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 0.2 mL double distilled water (DDW)
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存液
- Without preservative
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- SYN2 (Synapsin II (SYN2))
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别名
- Synapsin-2
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背景
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Synonyms: Synapsin-2
Description: Synapsins are a family of ten homologous neuronal phosphoproteins evolutionarily conserved in invertebrate and vertebrate organisms. Synapsins appear to be crucial determinants for the fine-tuning of synaptic transmission and for synaptic remodeling. This is particularly evident in several paradigms of short-term plasticity (STP), which are specifically affected by mutations or malfunctioning of synapsin proteins. Notably, knockout of synapsin-2 in mice causes fully generalized forebrain seizures from the age of 2 months1.All synapsins, including synapsin-2, are composed of a highly homologous N-terminal region, and a more variable C-terminus. The N-terminal homologous region can be divided in three domains, namely domain A, B and C, which, except for domain B, are highly conserved across isoforms and species. Domain A is contains the phosphorylation site for PKA and CaMKI. Domain B, rich in small amino acids, is considered as a linker region connecting domain A to domain C. Domain C is a large region of about 300 amino acids, containing both hydrophobic and highly charged sequences with the potential to assume α-helix and β-sheet conformations. It shows extensive homology amongst the various members of the family, and mediates the core functions of synapsins1.
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基因ID
- 29179
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UniProt
- Q63537
抗原
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