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Stim2 抗体 (C-Term, Intracellular)

The 兔 多克隆 anti-Stim2 antibody (ABIN7885544) specifically detects Stim2 in WB, IHC, IF 和 IC. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7885544
发货至: 中国
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Quick Overview for Stim2 抗体 (C-Term, Intracellular) (ABIN7885544)

抗原

See all Stim2 抗体
Stim2 (Stromal Interaction Molecule 2 (Stim2))

适用

  • 37
  • 14
  • 10
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 34
  • 2
  • 1

克隆类型

  • 37
多克隆

标记

  • 26
  • 4
  • 3
  • 2
  • 1
  • 1
This Stim2 antibody is un-conjugated

应用范围

  • 33
  • 25
  • 17
  • 7
  • 6
  • 4
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunochromatography (IC)

质量等级

Carrier-free, KO Validated
  • 抗原表位

    • 8
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 583-597, C-Term, Intracellular

    原理

    A Rabbit Polyclonal Antibody to STIM2

    预测反应

    Rat,mouse,bovine - identical

    纯化方法

    Affinity purified on immobilized antigen.

    免疫原

    SAEKQWEVPDTASEC, corresponding to amino acid residues 583-597 of human STIM2

    亚型

    IgG
  • 应用备注

    WB: 1:200

    FC: The optimal concentration should be determined by the user

    ICC: 1:100

    IHC: 1:100

    IP: The optimal concentration should be determined by the user

    说明

    Negative Control: (ABIN7237296)

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    0.2 mL double distilled water (DDW)

    浓度

    1 mg/mL

    缓冲液

    PBS pH 7.4

    储存液

    Without preservative

    储存条件

    -20 °C

    储存方法

    The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
  • 抗原

    Stim2 (Stromal Interaction Molecule 2 (Stim2))

    别名

    Stromal interaction molecule 2

    背景

    Synonyms: Stromal interaction molecule 2

    Description: Cytosolic Ca2+ has long been known to act as a key second messenger in many intracellular pathways including synaptic transmission, muscle contraction, hormonal secretion, cell growth and proliferation.1,2 The mechanism controlling the influx of intracellular Ca2+ either by calcium-release-activated Ca2+ channels (CRAC) or from intracellular stores has lately become the focus of intense research.Recently, several key players of the store-operated complex have been identified: the Orai family consists of three members: Orai1-3, and the STIM family, which consists of two members, STIM1 and STIM2.3 Orai1 (also known as CRACM1) acts as the store-operated calcium channel (SOC) and STIM1 as the endoplasmic reticulum (ER) Ca2+ sensor.3,4While STIM1 appears to be localized intracellularly at the ER membrane and at a much lower extent on the cell surface of several cell types, STIM2 appears to be localized solely at the ER membrane.5 The function of STIM2 still remains elusive and several models have been suggested.6-8

    基因ID

    57620

    UniProt

    Q9P246

    途径

    TCR Signaling, BCR Signaling
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