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S1PR2 抗体 (2nd Cytoplasmic Loop)

The 兔 多克隆 anti-S1PR2 antibody is suitable to detect S1PR2 in samples from 人, 小鼠 和 大鼠. It has been validated for WB 和 IHC.
产品编号 ABIN7885537
发货至: 中国
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Quick Overview for S1PR2 抗体 (2nd Cytoplasmic Loop) (ABIN7885537)

抗原

See all S1PR2 抗体
S1PR2 (Sphingosine-1-Phosphate Receptor 2 (S1PR2))

适用

  • 24
  • 10
  • 7
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 26
  • 1

克隆类型

  • 27
多克隆

标记

  • 17
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This S1PR2 antibody is un-conjugated

应用范围

  • 16
  • 12
  • 7
  • 5
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)

质量等级

Carrier-free
  • 抗原表位

    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    2nd Cytoplasmic Loop, AA 129-146

    原理

    A Rabbit Polyclonal Antibody to Sphingosine 1-Phosphate Receptor 2

    预测反应

    Rat - 17,18 amino acid residues identical, human - 16

    纯化方法

    Affinity purified on immobilized antigen.

    免疫原

    ERQVALAKVKLYGSDKSC, corresponding to amino acid residues 129-146 of mouse S1PR2

    亚型

    IgG
  • 应用备注

    WB: 1:200

    FC: The optimal concentration should be determined by the user

    ICC: The optimal concentration should be determined by the user

    IHC: 1:100

    IP: The optimal concentration should be determined by the user

    说明

    Negative Control: (ABIN7237271)

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    0.2 mL double distilled water (DDW)

    浓度

    1 mg/mL

    缓冲液

    PBS pH 7.4

    储存液

    Without preservative

    储存条件

    -20 °C

    储存方法

    The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
  • 抗原

    S1PR2 (Sphingosine-1-Phosphate Receptor 2 (S1PR2))

    别名

    Sphingosine 1-phosphate receptor 2

    背景

    Synonyms: Sphingosine 1-phosphate receptor 2, S1P2, Endothelial differentiation G-protein coupled receptor 5, Lysophospholipid receptor B2, LPB2

    Description: Lysophospholipids constitute a group of important lipid mediators, lysophosphatidic acid (LPA) a glycerolysophospholipid and sphingosine 1-phosphate (S1P), a lysosphingolipid. Sphingosine 1-phosphate is a bioactive lipid derived from metabolism of sphingomyelin1. Sphingosine 1-phosphate is implicated in the regulation of many cellular functions including proliferation, apoptosis, survival, adhesion, differentiation, and migration2.Sphingosine 1-phosphate exerts its activity through five distinct G-protein-coupled receptors, (also named endothelial differentiation gene receptors - EDG), S1PR1 (EDG-1), S1PR2 (EDG-5), S1PR3 (EDG-3), S1PR4 (EDG-6), and S1PR5 (EDG-8)3.Sphingosine 1-phosphate receptor 2 (S1PR2) is ubiquitously expressed. S1PR2 mRNA was detected in the brain, heart, spleen, liver, lung, thymus, kidney and skeletal muscle4. Unlike S1PR1, knockout of SIPR2 gene is not lethal5.

    基因ID

    14739

    UniProt

    P52592

    途径

    Synaptic Membrane
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