Neuropilin 1 抗体 (Extracellular, N-Term)
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Quick Overview for Neuropilin 1 抗体 (Extracellular, N-Term) (ABIN7885191)
抗原
See all Neuropilin 1 (NRP1) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 502-514, Extracellular, N-Term
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原理
- A Rabbit Polyclonal Antibody to Neuropilin-1
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预测反应
- Rat,mouse - identical
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- (C)GGKHRENKVFMRK, corresponding to amino acid residues 502-514 of human neuropilin-1
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亚型
- IgG
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anti-Neuropilin 1 (NRP1) (AA 646-814) antibody
NRP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neuropilin 1 (NRP1) (AA 646-814) antibodyNRP1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C2 unconjugated
anti-Neuropilin 1 (NRP1) (AA 22-131) antibodyNRP1 适用: 人 WB, IP, ELISA 宿主: 小鼠 Monoclonal 1B3 unconjugated
anti-Neuropilin 1 (NRP1) (AA 21-250) antibodyNRP1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Neuropilin 1 (NRP1) antibodyNRP1 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Neuropilin 1 (NRP1) (AA 722-750), (C-Term) antibodyNRP1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22995 unconjugated
anti-Neuropilin 1 (NRP1) (AA 722-750) antibodyNRP1 适用: 人 WB, IHC, FACS, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Neuropilin 1 (NRP1) (AA 45-59) antibodyNRP1 适用: 人 WB, FACS, ELISA 宿主: 小鼠 Monoclonal 5B1E11 unconjugated
anti-Neuropilin 1 (NRP1) antibodyNRP1 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 24GB180 unconjugated Recombinant Antibody
anti-Neuropilin 1 (NRP1) (AA 504-827) antibodyNRP1 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 1:200
FC: 2.5 μg per reaction
ICC: 1:25
IHC: The optimal concentration should be determined by the user
IP: The optimal concentration should be determined by the user
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说明
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Negative Control: (ABIN7236114)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 0.2 mL double distilled water (DDW)
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存液
- Without preservative
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- Neuropilin 1 (NRP1)
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别名
- Vascular endothelial cell growth factor 165 receptor
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背景
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Synonyms: Vascular endothelial cell growth factor 165 receptor, VEGF165R, CD304
Description: Neuropilins (NRPs) are co-receptors for class 3 semaphorins, polypeptides with key roles in axonal guidance, and for members of the VEGF (vascular endothelial growth factor) family of angiogenic cytokines.Neuropilin 1 (NRP1) is a transmembrane glycoprotein and comprises a large extracellular region containing multiple domains, a single transmembrane domain and a small cytoplasmic domain, also with a number of protein interacting domains.Class 3 semaphorins bind NRP1 (and NRP2) with different, and partially overlapping, specificities and affinities. Plexin A1 and Plexin A2 are the major signaling receptors for class 3 semaphorins, and complex with NRPs and semaphorins to form a holoreceptor essential for mediating effects of semaphorins on growth-cone collapse and axonal guidance in neurogenesis. The major VEGF-A signaling receptor, VEGF receptor 2, forms complexes with NRP1 and is important for optimal VEGFR2 signaling and function in endothelial cells.Targeted disruption of the NRP1 gene has demonstrated an essential dual role of these molecules in neurogenesis and cardiovascular development. NRP1-null mice die with a spectrum of cardiovascular and neuronal defects1.
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基因ID
- 8829
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UniProt
- O14786
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途径
- Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals
抗原
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