GALR2 抗体 (3rd Intracellular Loop)
Our Local Distributor
北京 101111
Quick Overview for GALR2 抗体 (3rd Intracellular Loop) (ABIN7885009)
抗原
See all GALR2 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
-
-
抗原表位
- 3rd Intracellular Loop, AA 223-235
-
原理
- A Rabbit Polyclonal Antibody to Galanin Receptor Type 2
-
预测反应
- Rat - identical, human - 11,13 amino acid residues identical
-
纯化方法
- Affinity purified on immobilized antigen.
-
免疫原
- (C)GSGSQRAKRKVTR, corresponding to amino acid residues 223-235 of mouse Galanin receptor type 2
-
亚型
- IgG
-
-
anti-Galanin Receptor 2 (GALR2) (AA 51-150) antibody
GALR2 适用: 人, 小鼠, 大鼠 WB, FACS, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Galanin Receptor 2 (GALR2) (C-Term) antibodyGALR2 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Galanin Receptor 2 (GALR2) (Transmembrane Domain) antibodyGALR2 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Galanin Receptor 2 (GALR2) (Internal Region) antibodyVerified GALR2 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Galanin Receptor 2 (GALR2) (AA 282-387) antibodyGALR2 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Galanin Receptor 2 (GALR2) antibodyGALR2 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Galanin Receptor 2 (GALR2) (3rd Intracellular Loop), (AA 223-235) antibodyGALR2 适用: 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
WB: 1:200
FC: The optimal concentration should be determined by the user
ICC: The optimal concentration should be determined by the user
IHC: 1:100
IP: The optimal concentration should be determined by the user
-
说明
-
Negative Control: (ABIN7235477)
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- 0.2 mL double distilled water (DDW)
-
浓度
- 1 mg/mL
-
缓冲液
- PBS pH 7.4
-
储存液
- Without preservative
-
储存条件
- -20 °C
-
储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
-
-
- GALR2 (Galanin Receptor 2 (GALR2))
-
别名
- Galanin receptor type 2
-
背景
-
Synonyms: Galanin receptor type 2, GALNR2, GAL2R
Description: Galanin is a neuropeptide, consisting of 29-30 amino acid residues, involved in the regulation of cognition, mood, feeding, seizure activity and pain. Galanin exerts its action via three known receptors, the Galanin receptor type 1 (GALR1), Galanin receptor type 2 (GALR2) and Galanin receptor type 3 (GALR3). The Galanin receptors belong to the G-protein coupled receptor superfamily.1-4GALR2 is widely expressed in the brain (with highest levels of mRNA found in the hypothalamus, hippocampus, amygdala and pyriform cortex) and in peripheral tissues such as the small intestine, heart, kidney, and liver. High levels of GALR2 expression were also found in rat dorsal root ganglia.1GALR2 activation increases inositol phosphate hydrolysis, mediates the release of Ca2+ into the cytoplasm from intracellular stores, and opens Ca2+-dependent chloride channels in a PTX-resistant manner, indicating that GALR2 couples to Gq/11 proteins.5
-
基因ID
- 14428
-
UniProt
- O88854
-
途径
- cAMP Metabolic Process, Inositol Metabolic Process, Feeding Behaviour
抗原
-
