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GPR174 抗体 (Extracellular Loop)

This 兔 多克隆 antibody specifically detects GPR174 in WB, FACS 和 LCI. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7884975
发货至: 中国
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Quick Overview for GPR174 抗体 (Extracellular Loop) (ABIN7884975)

抗原

See all GPR174 抗体
GPR174 (G Protein-Coupled Receptor 174 (GPR174))

适用

  • 33
  • 8
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 33

克隆类型

  • 33
多克隆

标记

  • 23
  • 3
  • 2
  • 2
  • 2
  • 1
This GPR174 antibody is un-conjugated

应用范围

  • 23
  • 17
  • 7
  • 6
  • 4
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS), Live Cell Imaging (LCI)

质量等级

Carrier-free
  • 抗原表位

    • 9
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 160-175, Extracellular Loop

    原理

    A Rabbit Polyclonal Antibody to GPR174

    预测反应

    Human - 15,16 amino acid residues identical, mouse,rat - 13

    纯化方法

    Affinity purified on immobilized antigen.

    免疫原

    (C)DTSGNRTK(S)FVDLPTR, corresponding to amino acid residues 160 - 175 of human GPR174

    亚型

    IgG
  • 应用备注

    WB: 1:400

    FC: 5 μg per reaction

    ICC: The optimal concentration should be determined by the user

    IHC: The optimal concentration should be determined by the user

    IP: The optimal concentration should be determined by the user

    说明

    Negative Control: (ABIN7235384)

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    0.2 mL double distilled water (DDW)

    浓度

    1 mg/mL

    缓冲液

    PBS pH 7.4

    储存液

    Without preservative

    储存条件

    -20 °C

    储存方法

    The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
  • 抗原

    GPR174 (G Protein-Coupled Receptor 174 (GPR174))

    别名

    G-protein coupled receptor 174

    背景

    Synonyms: G-protein coupled receptor 174, LYPSR3, GPCR17, FKSG79

    Description: GPR174 (LysoPS, LYPSR3), is one of three lysophosphatidyl serine receptors, belonging to the superfamily of G-protein coupled receptors. Lysophospholipids are a diverse group of small, membrane-derived phospholipids that act as extracellular signals1.Activation of GPR174 leads to an increase in cAMP cellular levels, leading to cellular morphological changes, cell to cell adhesion, and delays in cell proliferation2.GPR174 is reported to be a genetic risk locus for Graves disease, an autoimmune disorder that causes hyperthyroidism3 and as a negative regulator of T-cells activation4.

    基因ID

    84636

    UniProt

    Q9BXC1
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