GPR174 抗体 (Extracellular Loop)
Our Local Distributor
北京 101111
Quick Overview for GPR174 抗体 (Extracellular Loop) (ABIN7884975)
抗原
See all GPR174 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
-
-
抗原表位
- AA 160-175, Extracellular Loop
-
原理
- A Rabbit Polyclonal Antibody to GPR174
-
预测反应
- Human - 15,16 amino acid residues identical, mouse,rat - 13
-
纯化方法
- Affinity purified on immobilized antigen.
-
免疫原
- (C)DTSGNRTK(S)FVDLPTR, corresponding to amino acid residues 160 - 175 of human GPR174
-
亚型
- IgG
-
-
-
-
应用备注
-
WB: 1:400
FC: 5 μg per reaction
ICC: The optimal concentration should be determined by the user
IHC: The optimal concentration should be determined by the user
IP: The optimal concentration should be determined by the user
-
说明
-
Negative Control: (ABIN7235384)
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- 0.2 mL double distilled water (DDW)
-
浓度
- 1 mg/mL
-
缓冲液
- PBS pH 7.4
-
储存液
- Without preservative
-
储存条件
- -20 °C
-
储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
-
-
- GPR174 (G Protein-Coupled Receptor 174 (GPR174))
-
别名
- G-protein coupled receptor 174
-
背景
-
Synonyms: G-protein coupled receptor 174, LYPSR3, GPCR17, FKSG79
Description: GPR174 (LysoPS, LYPSR3), is one of three lysophosphatidyl serine receptors, belonging to the superfamily of G-protein coupled receptors. Lysophospholipids are a diverse group of small, membrane-derived phospholipids that act as extracellular signals1.Activation of GPR174 leads to an increase in cAMP cellular levels, leading to cellular morphological changes, cell to cell adhesion, and delays in cell proliferation2.GPR174 is reported to be a genetic risk locus for Graves disease, an autoimmune disorder that causes hyperthyroidism3 and as a negative regulator of T-cells activation4.
-
基因ID
- 84636
-
UniProt
- Q9BXC1
抗原
-