DLG3 抗体 (N-Term)
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Quick Overview for DLG3 抗体 (N-Term) (ABIN7884915)
抗原
See all DLG3 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 93-124, N-Term
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原理
- A Rabbit Polyclonal Antibody to SAP-102
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预测反应
- Rat,mouse - 26,32 amino acid residues identical
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纯化方法
- The serum was depleted of anti-GST antibodies by affinity chromatography on immobilized GST and then the IgG fraction was purified on immobilized antigen.
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免疫原
- GST fusion protein with the sequence KSTPKLNGSGPSWWPECTCTNRDWYEQVNGSD, corresponding to amino acid residues 93-124 of human SAP102
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亚型
- IgG
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anti-Discs, Large Homolog 3 (DLG3) (AA 501-600) antibody
DLG3 适用: 人, 大鼠 WB, ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Discs, Large Homolog 3 (DLG3) (AA 281-380) antibodyDLG3 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 2B6 unconjugated
anti-Discs, Large Homolog 3 (DLG3) (AA 1-817) antibodyDLG3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Discs, Large Homolog 3 (DLG3) (AA 464-817) antibodyDLG3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Discs, Large Homolog 3 (DLG3) (AA 749-817) antibodyDLG3 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Discs, Large Homolog 3 (DLG3) (AA 627-802) antibodyDLG3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Discs, Large Homolog 3 (DLG3) (AA 201-250) antibodyDLG3 适用: 人, 大鼠, 小鼠, Cow, 豚鼠, 兔, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Discs, Large Homolog 3 (DLG3) (AA 108-157) antibodyDLG3 适用: 人, 大鼠, 小鼠, Cow, 豚鼠, 兔, 犬, 斑马鱼, Pig, 猴, Bat, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Discs, Large Homolog 3 (DLG3) (AA 648-697) antibodyDLG3 适用: 人, 大鼠, 小鼠, Cow, 豚鼠, 兔, 犬, 马, 斑马鱼, Pig, 猴, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Discs, Large Homolog 3 (DLG3) (AA 58-107) antibodyDLG3 适用: 人, 大鼠, 小鼠, Cow, 豚鼠, 兔, Pig, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 1:400
FC: The optimal concentration should be determined by the user
ICC: The optimal concentration should be determined by the user
IHC: The optimal concentration should be determined by the user
IP: The optimal concentration should be determined by the user
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说明
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Negative Control: (ABIN7235227)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 0.2 mL double distilled water (DDW)
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存液
- Without preservative
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- DLG3 (Discs, Large Homolog 3 (DLG3))
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别名
- Synapse-associated protein 102
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背景
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Synonyms: Synapse-associated protein 102, SAP-102, Discs large homolog 3, DLG3, NE-DLG
Description: SAP-102 (also known as DLG3) is a PDZ containing domain protein that is also a member of the membrane-associated guanylate kinase (MAGUK) family of multi-domain adaptor proteins1,2.PDZ domains are conserved protein domains of about 90 amino acids involved in protein-protein recognition, protein targeting and assembly of multi-protein complexes. The name PDZ derives from the first three proteins in which these domains were identified: PSD-95 (a 95 kDa protein involved in signaling at the post-synaptic density), DLG (the Drosophila melanogaster Discs large protein) and ZO-1 (the zonula occludens 1 protein involved in maintenance of epithelial polarity)1,2.MAGUKs are scaffolding proteins that comprise several modular protein binding motifs including one or more PDZ domains, a Src homology 3 (SH3) domain, and a catalytically inactive guanylate kinase-like domain1,2.The multidomain nature of PDZ-containing proteins enables them to interact with multiple binding partners and hence organize larger signaling protein complexes.SAP-102 has been shown to participate in the postsynaptic density, a dedicated structure formed in postsynaptic nerve terminals that includes a specialized assembly of ion channels, receptors and signaling molecules that are involved in information processing and the modulation of synaptic plasticity1,2. Moreover, mutations in the SAP102 gene have been linked with a form of mental retardation3.
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基因ID
- 1741
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UniProt
- Q92796
抗原
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