Complexin 1 抗体 (Intracellular, N-Term)
Our Local Distributor
北京 101111
Quick Overview for Complexin 1 抗体 (Intracellular, N-Term) (ABIN7884894)
抗原
See all Complexin 1 (CPLX1) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
-
-
抗原表位
- AA 14-27, Intracellular, N-Term
-
原理
- A Rabbit Polyclonal Antibody to Complexin-1 and Complexin-2
-
预测反应
- Complexin 1: Mouse,human - identicalComplexin 2: Rat,mouse,human - 13,14 amino acid residues identical
-
纯化方法
- Affinity purified on immobilized antigen.
-
免疫原
- (C)KDMGKMLGGDEEKD, corresponding to amino acid residues 14-27 of rat Complexin-1
-
亚型
- IgG
-
-
anti-Complexin 1 (CPLX1) (AA 31-100) antibody
CPLX1 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Complexin 1 (CPLX1) (AA 1-134) antibodyCPLX1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Complexin 1 (CPLX1) (N-Term) antibodyCPLX1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Complexin 1 (CPLX1) (AA 1-134) antibodyCPLX1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Complexin 1 (CPLX1) (AA 33-60) antibodyCPLX1 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB23961 unconjugated
anti-Complexin 1 (CPLX1) (AA 39-69), (Middle Region) antibodyCPLX1 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Complexin 1 (CPLX1) (AA 1-134) antibody (APC)CPLX1 适用: 人 IHC, IF, ICC, FACS 宿主: 兔 Polyclonal APC
anti-Complexin 1 (CPLX1) (AA 1-134) antibody (PE)CPLX1 适用: 人 IHC, IF, ICC, FACS 宿主: 兔 Polyclonal PE
-
-
应用备注
-
WB: 1:200
FC: The optimal concentration should be determined by the user
ICC: The optimal concentration should be determined by the user
IHC: The optimal concentration should be determined by the user
IP: The optimal concentration should be determined by the user
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- 0.2 mL double distilled water (DDW)
-
浓度
- 1 mg/mL
-
缓冲液
- PBS pH 7.4
-
储存液
- Without preservative
-
储存条件
- -20 °C
-
储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
-
-
- Complexin 1 (CPLX1)
-
别名
- Complexin 1
-
背景
-
Synonyms: Complexin 1, Complexin I, Synaphin-2, Complexin 2, Complexin II, Synaphin-1
Description: Complexins (1 through 4) are small cytosolic proteins that bind tightly to a complex of SNARE proteins to regulate synaptic vesicle membrane fusion via its interaction with synaptotagmin. Complexins activate the quick release of neurotransmitters, triggered by calcium release. They also regulate the "spontaneous release" of neurotransmitters1-3.Complexins are evolutionarily conserved in mammals, Drosophila, and Caenorhabditis elegans1,2. They are divided into four structural domains: flexible N- and C-terminal domains, an accessory domain, and a central α-helical domain. The N-terminal domain plays a role in activation of fast synchronous release in murine neurons and in isolated chromaffin cells. The C-terminal domain binds to phospholipids and is important for regulating spontaneous release in neuronal cultures and suppressing Ca2+-independent fusion in vitro. The accessory domain is necessary for regulating spontaneous release and the central domain is required for all functions1,2.
-
基因ID
- 64833, 116657
-
UniProt
- P63041, P84087
-
途径
- Hormone Transport, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
抗原
-
