CD97 抗体 (Extracellular, N-Term)
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Quick Overview for CD97 抗体 (Extracellular, N-Term) (ABIN7884854)
抗原
See all CD97 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 499-512, Extracellular, N-Term
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原理
- A Rabbit Polyclonal Antibody to CD97/ADGRE5
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预测反应
- Human only
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- (C)KSDSDRGGHWATEG, corresponding to amino acid residues 499-512 of human CD97/ADGRE5
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亚型
- IgG
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anti-CD97 (CD97) (AA 419-552) antibody
CD97 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 6D7E6 unconjugated
anti-CD97 (CD97) (AA 741-835) antibodyCD97 适用: 人 ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-CD97 (CD97) (AA 421-529) antibodyCD97 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 5D5 unconjugated
anti-CD97 (CD97) (AA 58-260) antibodyCD97 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C3 unconjugated
anti-CD97 (CD97) antibodyCD97 适用: 人 IHC, ELISA, IF 宿主: 兔 Monoclonal 3A7 unconjugated Recombinant Antibody
anti-CD97 (CD97) (AA 240-435) antibodyCD97 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CD97 (CD97) (N-Term) antibodyCD97 适用: 人 IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD97 (CD97) antibodyKD Validated CD97 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB3390 unconjugated Recombinant Antibody
anti-CD97 (CD97) antibodyKD Validated CD97 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB3740 unconjugated Recombinant Antibody
anti-CD97 (CD97) antibody (FITC)CD97 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-180 FITC
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应用备注
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WB: 1:200
FC: 2.5 μg per reaction
ICC: The optimal concentration should be determined by the user
IHC: The optimal concentration should be determined by the user
IP: The optimal concentration should be determined by the user
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 0.2 mL double distilled water (DDW)
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存液
- Without preservative
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- CD97
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别名
- Adhesion G protein-coupled receptor E5
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背景
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Synonyms: Adhesion G protein-coupled receptor E5, Leukocyte antigen CD97, Seven-transmembrane heterodimeric receptor associated with inflammation
Description: CD97, encoded by the adhesion G protein-coupled receptor 5 (ADGRE5) gene, is a member of the epidermal growth factor (EGF) seven transmembrane receptor family, belonging to the adhesion family of G protein-coupled receptors (GPCRs)1. CD97 is widely expressed on the surface of lymphoid cells, macrophages, smooth muscle cells and several types of tumor cells and acts through binding of decay accelerating factor (CD55) and dermatan sulfate2.In the immune system, CD97 is known as a critical mediator of host defense. Upon lymphoid, myeloid cells and neutrophil activation, CD97 is upregulated to promote adhesion and migration to sites of inflammation3. Antibodies against CD97 have been demonstrated to diminish various inflammatory disorders by depleting granulocytes and the interaction between CD97 and its ligand CD55 regulates T-cell activation and increases proliferation and cytokine production4.Changes in the expression of CD97 have been described in auto-inflammatory diseases, such as rheumatoid arthritis and multiple sclerosis. Outside the immune system, CD97 is likely involved in cell-cell interactions and ectopic CD97 expression leading to enhanced cell-cell aggregation5.
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基因ID
- 976
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UniProt
- P48960
抗原
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