CD81 抗体 (Extracellular, Loop 2)
Our Local Distributor
北京 101111
Quick Overview for CD81 抗体 (Extracellular, Loop 2) (ABIN7884853)
抗原
See all CD81 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
-
-
抗原表位
- AA 190-201, Extracellular, Loop 2
-
原理
- A Rabbit Polyclonal antibody to CD81 (extracellular)
-
预测反应
- Mouse,rat - 11 out of 12 amino acid residues identical
-
纯化方法
- Affinity purified on immobilized antigen.
-
免疫原
- CHQKIDDLFSGK, corresponding to amino acid residues 190 - 201 of human CD81
-
亚型
- IgG
-
-
anti-CD81 (CD81) antibody
KO Validated CD81 适用: 人 FACS, WB, IF, ICC, IHC (p), BP 宿主: 兔 Polyclonal unconjugated
anti-CD81 (CD81) (AA 1-100) antibodyCD81 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD81 (CD81) (AA 190-201), (Extracellular), (Loop 2) antibodyCD81 适用: 人 FACS, WB, IHC, LCI 宿主: 兔 Polyclonal unconjugated
anti-CD81 (CD81) (AA 190-201), (Extracellular), (Loop 2) antibody (FITC)CD81 适用: 人 FACS, LCI 宿主: 兔 Polyclonal FITC
anti-CD81 (CD81) antibodyCD81 适用: 人, 小鼠, 大鼠 FACS, WB, IHC, IF, Func 宿主: 小鼠 Monoclonal 1-3-3-22 unconjugated
anti-CD81 (CD81) antibodyCD81 适用: 人, 小鼠, 大鼠 FACS, WB 宿主: 兔 Monoclonal C81-2885R unconjugated Recombinant Antibody
anti-CD81 (CD81) antibodyCD81 适用: 人 FACS, WB, IHC, ELISA 宿主: 兔 Monoclonal 9F7 unconjugated Recombinant Antibody
anti-CD81 (CD81) antibody (PE)CD81 适用: 人, 兔, Cat FACS 宿主: 小鼠 Monoclonal M38 PE
anti-CD81 (CD81) antibodyCD81 适用: 人, 兔, Cat FACS, WB, IP, ICC, IHC (p) 宿主: 小鼠 Monoclonal M38 unconjugated
anti-CD81 (CD81) antibody (FITC)CD81 适用: 人, 兔, Cat FACS 宿主: 小鼠 Monoclonal M38 FITC
-
-
应用备注
-
WB: 1:200-1:400
FC: 2.5-5 μg per reaction
ICC: The optimal concentration should be determined by the user
IHC: 1:300
IP: The optimal concentration should be determined by the user
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- 0.2 mL double distilled water (DDW)
-
浓度
- 1 mg/mL
-
缓冲液
- PBS pH 7.4
-
储存液
- Without preservative
-
储存条件
- -20 °C
-
储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
-
-
- CD81
-
别名
- Tetraspanin-28
-
背景
-
Synonyms: Tetraspanin-28, TSPAN28, Target of the Antiproliferative Antibody 1, TAPA-1
Description: Cluster of differentiation 81, CD81, also known as Tetraspanin-28, Tspan28, and target of the antiproliferative antibody 1, TAPA-1, is a transmembrane (TM) protein, member of the tetraspanin family, and plays a role in intercellular interactions and cellular trafficking.1CD81 is composed of 236 amino acids, four TM regions, intracellular N- and C-termini, small (EC1) and large (EC2) extracellular loops, a short intracellular loop between TM2 and TM3, and is characterized by a bound cholesterol molecule in an intramembrane pocket between the two pairs of TM helices capped by the EC2 domain. The binding of cholesterol alters the conformation of the protein, a process which is exploited by certain viruses to enter cells. CD81 serves as a co-receptor for several viruses, including hepatitis C (HCV), human immunodeficiency virus type 1 (HIV-1), herpes simplex virus 1 (HSV-1), influenza A (IAV), and Chikungunya, as well as certain bacteria and parasites. CD81 can interact with other TM proteins to form clusters and higher-order protein complexes.1,2CD81 is highly conserved in mammals, expressed on all primary B-lineage cells from early B-cell development stages, and associates with CD19 on the cell surface. CD81 engagement on mature human B-cells induces an antiproliferative effect.3CD81 is involved in neurotransmission, cell signaling, cell proliferation, and protein trafficking, as well as the immune, reproductive, genitourinary, and auditory systems. CD81 is also implicated in oncology, viral infection, and inflammation.1,2
-
基因ID
- 975
-
UniProt
- P60033
-
途径
- Inositol Metabolic Process, Hepatitis C
抗原
-
