Aquaporin 8 抗体 (Intracellular, N-Term)
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Quick Overview for Aquaporin 8 抗体 (Intracellular, N-Term) (ABIN7884772)
抗原
See all Aquaporin 8 (AQP8) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 14-28, Intracellular, N-Term
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原理
- A Rabbit Polyclonal Antibody to Aquaporin 8 Channel
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预测反应
- Unlikely to recognize mouse,human samples
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- (C)REIKGKETNMADSYH, corresponding to amino acid residues 14-28 of rat AQP8
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亚型
- IgG
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anti-Aquaporin 8 (AQP8) (AA 1-255) antibody
AQP8 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A1 unconjugated
anti-Aquaporin 8 (AQP8) (N-Term) antibodyAQP8 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 8 (AQP8) (AA 50-150) antibodyAQP8 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 8 (AQP8) (AA 14-28), (Intracellular), (N-Term) antibodyAQP8 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 8 (AQP8) (AA 1-255) antibodyAQP8 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1F8 unconjugated
anti-Aquaporin 8 (AQP8) antibodyAQP8 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 8 (AQP8) (AA 129-228) antibodyAQP8 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 1:200-1:400
FC: The optimal concentration should be determined by the user
ICC: The optimal concentration should be determined by the user
IHC: 1:100
IP: The optimal concentration should be determined by the user
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说明
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Negative Control: (ABIN7234779)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 0.2 mL double distilled water (DDW)
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存液
- Without preservative
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- Aquaporin 8 (AQP8)
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别名
- AQP8
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背景
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Synonyms: AQP8
Description: Aquaporin 8 (AQP-8) belongs to a family of membrane proteins that allow passage of water and certain other solutes through biological membranes.1 The family is composed of 13 members (AQP-0 to AQP-12). Little is known about the function of the two newest members, AQP-11 and AQP-12.The aquaporins can be divided into two functional groups based on their permability characteristics: the aquaporins that are permeated primarily by water and include besides AQP-8, AQP-1, AQP-2, AQP4 and AQP-5, and the aquaglyceroporins that are permeated by water and other small solutes such as glycerol. This last group includes AQP-3, AQP-7, AQP-9 and AQP-10.The proteins present a conserved structure of six transmembrane domains with intracellular N- and C-termini. The functional channel is a tetramer but each subunit has a separate pore and therefore the functional channel unit, contains four pores.2AQP-8 is expressed along the gastrointestinal tract including small intestine, colon, pancreas and liver and also in other organs such as testis, lung and kidney.The physiological function of AQP-8 is not entirely clear but studies suggest that it has an important role in colonic water adsorption and hepatocyte bile formation.3,4 Interestingly, AQP-8 expression is markedly altered in gastrointestinal disorders such as ulcerative colitis and inflammatory bowel disease.5
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基因ID
- 29172
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UniProt
- P56405
抗原
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