Aquaporin 7 抗体 (Intracellular, N-Term)
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Quick Overview for Aquaporin 7 抗体 (Intracellular, N-Term) (ABIN7884771)
抗原
See all Aquaporin 7 (AQP7) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 7-24, Intracellular, N-Term
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原理
- A Rabbit Polyclonal Antibody to Aquaporin 7 Channel
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预测反应
- 18 amino acid residues identical,Mouse - 15, human - 11
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- ENIQSVLQKTWVREFLAE, corresponding to amino acid residues 7-24 of rat AQP7
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亚型
- IgG
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应用备注
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WB: 1:500
FC: The optimal concentration should be determined by the user
ICC: 1:800
IHC: 1:100
IP: The optimal concentration should be determined by the user
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说明
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Negative Control: (ABIN7234775)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 0.2 mL double distilled water (DDW)
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存液
- Without preservative
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- Aquaporin 7 (AQP7)
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别名
- AQP7
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背景
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Synonyms: AQP7, Aquaglyceroporin-7, AQPap, Aquaporin adipose
Description: Aquaporin 7 (AQP-7) belongs to a family of membrane proteins that allow passage of water and certain other solutes through biological membranes. The family is composed of 13 members (AQP-0 to AQP-12). Little is known about the function of the two newest members, AQP-11 and AQP-12.The aquaporins can be divided into two functional groups based on their permeability characteristics: the aquaporins that are only permeated by water and the aquaglyceroporins that are permeated by water and other small solutes such as glycerol. This last group includes AQP-7, AQP-3, AQP-9 and AQP-10.The proteins present a conserved structure of six transmembrane domains with intracellular N- and C-termini. The functional channel is a tetramer but each subunit has a separate pore and therefore the functional channel unit contains four pores.AQP-7 is expressed in ovary, testis, kidney and adipose tissue.The function of AQP-7 in adipose tissue attracted much interest as mice deficient in AQP-7 developed adult-onset obesity and Type 2 Diabetes. AQP-7 modulates adipocyte glycerol permeability thereby controlling triglyceride accumulation and fat cell size.
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基因ID
- 29171
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UniProt
- P56403
抗原
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