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Aquaporin 7 抗体 (Intracellular, N-Term)

This 兔 多克隆 antibody specifically detects Aquaporin 7 in WB, IHC, IF 和 IC. It exhibits reactivity toward 大鼠 和 小鼠.
产品编号 ABIN7884771
发货至: 中国
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Quick Overview for Aquaporin 7 抗体 (Intracellular, N-Term) (ABIN7884771)

抗原

See all Aquaporin 7 (AQP7) 抗体
Aquaporin 7 (AQP7)

适用

  • 33
  • 23
  • 22
  • 3
  • 3
大鼠, 小鼠

宿主

  • 35
  • 1

克隆类型

  • 36
多克隆

标记

  • 13
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Aquaporin 7 antibody is un-conjugated

应用范围

  • 14
  • 13
  • 13
  • 13
  • 8
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunochromatography (IC)

质量等级

Carrier-free
  • 抗原表位

    • 16
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 7-24, Intracellular, N-Term

    原理

    A Rabbit Polyclonal Antibody to Aquaporin 7 Channel

    预测反应

    18 amino acid residues identical,Mouse - 15, human - 11

    纯化方法

    Affinity purified on immobilized antigen.

    免疫原

    ENIQSVLQKTWVREFLAE, corresponding to amino acid residues 7-24 of rat AQP7

    亚型

    IgG
  • 应用备注

    WB: 1:500

    FC: The optimal concentration should be determined by the user

    ICC: 1:800

    IHC: 1:100

    IP: The optimal concentration should be determined by the user

    说明

    Negative Control: (ABIN7234775)

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    0.2 mL double distilled water (DDW)

    浓度

    1 mg/mL

    缓冲液

    PBS pH 7.4

    储存液

    Without preservative

    储存条件

    -20 °C

    储存方法

    The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
  • 抗原

    Aquaporin 7 (AQP7)

    别名

    AQP7

    背景

    Synonyms: AQP7, Aquaglyceroporin-7, AQPap, Aquaporin adipose

    Description: Aquaporin 7 (AQP-7) belongs to a family of membrane proteins that allow passage of water and certain other solutes through biological membranes. The family is composed of 13 members (AQP-0 to AQP-12). Little is known about the function of the two newest members, AQP-11 and AQP-12.The aquaporins can be divided into two functional groups based on their permeability characteristics: the aquaporins that are only permeated by water and the aquaglyceroporins that are permeated by water and other small solutes such as glycerol. This last group includes AQP-7, AQP-3, AQP-9 and AQP-10.The proteins present a conserved structure of six transmembrane domains with intracellular N- and C-termini. The functional channel is a tetramer but each subunit has a separate pore and therefore the functional channel unit contains four pores.AQP-7 is expressed in ovary, testis, kidney and adipose tissue.The function of AQP-7 in adipose tissue attracted much interest as mice deficient in AQP-7 developed adult-onset obesity and Type 2 Diabetes. AQP-7 modulates adipocyte glycerol permeability thereby controlling triglyceride accumulation and fat cell size.

    基因ID

    29171

    UniProt

    P56403
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