Aquaporin 5 抗体 (C-Term, Intracellular)
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Quick Overview for Aquaporin 5 抗体 (C-Term, Intracellular) (ABIN7884769)
抗原
See all Aquaporin 5 (AQP5) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 251-265, C-Term, Intracellular
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原理
- A Rabbit Polyclonal Antibody to Aquaporin 5 Channel
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预测反应
- Mouse - identical, human - 10,16 amino acid residues identical
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- (C)DHREERKKTIELTAH corresponding to amino acid residues 251-265 of rat AQP5
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亚型
- IgG
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应用备注
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WB: 1:200
FC: The optimal concentration should be determined by the user
ICC: The optimal concentration should be determined by the user
IHC: The optimal concentration should be determined by the user
IP: The optimal concentration should be determined by the user
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说明
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Negative Control: (ABIN7234767)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 0.2 mL double distilled water (DDW)
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存液
- Without preservative
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- Aquaporin 5 (AQP5)
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别名
- AQP5
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背景
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Synonyms: AQP5
Description: The importance of the aquaporin water channels was underscored by awarding the 2003 Nobel Prize in Chemistry to Peter Agre "for the discovery of water channels". Today, eleven mammalian proteins that belong to the aquaporin family have been identified. The proteins present a conserved structure of six transmembrane domains with intracellular N- and C-termini. Aquaporin 5 (AQP5) is expressed in secretory glands, lung and eye, where it works in modulating the rate of fluid release. Since a number of pathological conditions including pulmonary edema, respiratory distress syndrome and congestive heart failure are characterized by disrupted fluid transport, it has been suggested that modulation of the expression of AQP5 could be a novel modality of treatment of the above illnesses. Indeed, several studies have shown that AQP5 expression is downregulated in animal models of acute lung infection.
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基因ID
- 25241
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UniProt
- P47864
抗原
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