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Aquaporin 5 抗体 (C-Term, Intracellular)

The 兔 多克隆 anti-Aquaporin 5 antibody is suitable to detect Aquaporin 5 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IHC, IF 和 IC.
产品编号 ABIN7884769
发货至: 中国
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Quick Overview for Aquaporin 5 抗体 (C-Term, Intracellular) (ABIN7884769)

抗原

See all Aquaporin 5 (AQP5) 抗体
Aquaporin 5 (AQP5)

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This Aquaporin 5 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunochromatography (IC)

质量等级

Carrier-free
  • 抗原表位

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    AA 251-265, C-Term, Intracellular

    原理

    A Rabbit Polyclonal Antibody to Aquaporin 5 Channel

    预测反应

    Mouse - identical, human - 10,16 amino acid residues identical

    纯化方法

    Affinity purified on immobilized antigen.

    免疫原

    (C)DHREERKKTIELTAH corresponding to amino acid residues 251-265 of rat AQP5

    亚型

    IgG
  • 应用备注

    WB: 1:200

    FC: The optimal concentration should be determined by the user

    ICC: The optimal concentration should be determined by the user

    IHC: The optimal concentration should be determined by the user

    IP: The optimal concentration should be determined by the user

    说明

    Negative Control: (ABIN7234767)

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    0.2 mL double distilled water (DDW)

    浓度

    1 mg/mL

    缓冲液

    PBS pH 7.4

    储存液

    Without preservative

    储存条件

    -20 °C

    储存方法

    The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
  • 抗原

    Aquaporin 5 (AQP5)

    别名

    AQP5

    背景

    Synonyms: AQP5

    Description: The importance of the aquaporin water channels was underscored by awarding the 2003 Nobel Prize in Chemistry to Peter Agre "for the discovery of water channels". Today, eleven mammalian proteins that belong to the aquaporin family have been identified. The proteins present a conserved structure of six transmembrane domains with intracellular N- and C-termini. Aquaporin 5 (AQP5) is expressed in secretory glands, lung and eye, where it works in modulating the rate of fluid release. Since a number of pathological conditions including pulmonary edema, respiratory distress syndrome and congestive heart failure are characterized by disrupted fluid transport, it has been suggested that modulation of the expression of AQP5 could be a novel modality of treatment of the above illnesses. Indeed, several studies have shown that AQP5 expression is downregulated in animal models of acute lung infection.

    基因ID

    25241

    UniProt

    P47864
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