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YTHDF2 抗体

This 兔 多克隆 antibody specifically detects YTHDF2 in WB, IF, FACS 和 IHC (p). It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7882713
发货至: 中国
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Quick Overview for YTHDF2 抗体 (ABIN7882713)

抗原

See all YTHDF2 抗体
YTHDF2 (YTH Domain Family, Member 2 (YTHDF2))

适用

  • 27
  • 7
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 26
  • 2

克隆类型

  • 25
  • 3
多克隆

标记

  • 18
  • 3
  • 2
  • 2
  • 2
  • 1
This YTHDF2 antibody is un-conjugated

应用范围

  • 24
  • 15
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 原理

    YTHDF2 Antibody

    序列

    NDDDFEPYLS PQARPNNAYT AMSD

    纯化方法

    Affinity purified

    免疫原

    Amino acids NDDDFEPYLSPQARPNNAYTAMSD from the human protein were used as the immunogen for the YTHDF2 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the YTHDF2 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the YTHDF2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    YTHDF2 (YTH Domain Family, Member 2 (YTHDF2))

    别名

    YTHDF2

    背景

    YTH N6-methyladenosine RNA binding protein 2 is a protein that in humans is encoded by the YTHDF2 gene. This gene encodes a member of the YTH (YT521-B homology) superfamily containing YTH domain. The YTH domain is typical for the eukaryotes and is particularly abundant in plants. The YTH domain is usually located in the middle of the protein sequence and may function in binding to RNA. In addition to a YTH domain, this protein has a proline rich region which may be involved in signal transduction. An Alu-rich domain has been identified in one of the introns of this gene, which is thought to be associated with human longevity. In addition, reciprocal translocations between this gene and the Runx1 (AML1) gene on chromosome 21 has been observed in patients with acute myeloid leukemia. This gene was initially mapped to chromosome 14, which was later turned out to be a pseudogene. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

    UniProt

    Q9Y5A9
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