Recombinant WT1 抗体
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北京 101111
Quick Overview for Recombinant WT1 抗体 (ABIN7882702)
抗原
See all WT1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant Wilms Tumor 1 Antibody
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纯化方法
- Protein G affinity chromatography
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免疫原
- A recombinant human protein was used as the immunogen for the recombinant Wilms Tumor 1 antibody.
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亚型
- IgG1, kappa
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应用备注
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Titering of the recombinant Wilms Tumor 1 antibody may be required for optimal performance.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the recombinant Wilms Tumor 1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- WT1 (Wilms Tumor 1 (WT1))
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别名
- Wilms Tumor 1
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背景
- Wilms Tumor is a transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA. [UniProt]
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UniProt
- P19544
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途径
- Tube Formation
抗原
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