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Recombinant WT1 抗体

The 小鼠 单克隆 anti-WT1 antibody is suitable to detect WT1 in samples from 人. It has been validated for IHC (p).
产品编号 ABIN7882702
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant WT1 抗体 (ABIN7882702)

抗原

See all WT1 抗体
WT1 (Wilms Tumor 1 (WT1))

抗体类型

Recombinant Antibody

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This WT1 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

MMWT1-1
  • 原理

    Recombinant Wilms Tumor 1 Antibody

    纯化方法

    Protein G affinity chromatography

    免疫原

    A recombinant human protein was used as the immunogen for the recombinant Wilms Tumor 1 antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Titering of the recombinant Wilms Tumor 1 antibody may be required for optimal performance.

    2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store the recombinant Wilms Tumor 1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    WT1 (Wilms Tumor 1 (WT1))

    别名

    Wilms Tumor 1

    背景

    Wilms Tumor is a transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA. [UniProt]

    UniProt

    P19544

    途径

    Tube Formation
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