WT1 抗体
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北京 101111
Quick Overview for WT1 抗体 (ABIN7882699)
抗原
See all WT1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- WT1 Antibody / Wilms Tumor 1
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纯化方法
- Protein A affinity chromatography
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免疫原
- Recombinant human protein was used as the immunogen for this WT1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the WT1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the WT1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- WT1 (Wilms Tumor 1 (WT1))
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别名
- WT1
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背景
- Recognizes a 47-55 kDa-tumor suppressor protein, identified as Wilm's Tumor (WT1) protein. The antibody reacts with all isoforms of the full-length WT1 and also identifies WT1 lacking exon 2-encoded amino acids, frequently found in subsets of sporadic Wilms tumor and mesothelioma. WT1 protein has been identified in proliferative mesothelial cells, malignant mesothelioma, ovarian carcinoma, gonadoblastoma, nephroblastoma, and desmoplastic small round cell tumor. Lung adenocarcinomas rarely stain positive with this antibody. WT1 protein expression in mesothelial cells has become a reliable marker for the diagnosis of mesotheliomas.
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UniProt
- P19544
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途径
- Tube Formation
抗原
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