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Vitamin D Receptor 抗体

The 兔 单克隆 anti-Vitamin D Receptor antibody is suitable to detect Vitamin D Receptor in samples from 人, 小鼠 和 大鼠. It has been validated for WB.
产品编号 ABIN7882684
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Vitamin D Receptor 抗体 (ABIN7882684)

抗原

See all Vitamin D Receptor (VDR) 抗体
Vitamin D Receptor (VDR)

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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单克隆

标记

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This Vitamin D Receptor antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

AAGE-22
  • 原理

    Vitamin D Receptor Antibody / VDR

    纯化方法

    Affinity purified

    免疫原

    A synthetic peptide specific to human Vitamin D Receptor / VDR was used as the immunogen for the Vitamin D Receptor antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the Vitamin D Receptor antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store the Vitamin D Receptor antibody at -20oC.
  • 抗原

    Vitamin D Receptor (VDR)

    别名

    Vitamin D Receptor

    物质类

    Chemical

    背景

    The VDR gene encodes vitamin D3 receptor, which is a member of the nuclear hormone receptor superfamily of ligand-inducible transcription factors. This receptor also functions as a receptor for the secondary bile acid, lithocholic acid. Downstream targets of vitamin D3 receptor are principally involved in mineral metabolism, though this receptor regulates a variety of other metabolic pathways, such as those involved in immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [RefSeq]

    UniProt

    P11473

    途径

    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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