UCP3 抗体
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Quick Overview for UCP3 抗体 (ABIN7882641)
抗原
See all UCP3 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- UCP3 Antibody / SLC25A9
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序列
- LDTAKVRLQI QGENQAVQTA RLVQYR
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids LDTAKVRLQIQGENQAVQTARLVQYR were used as the immunogen for the UCP3 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the UCP3 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the UCP3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- UCP3 (Uncoupling Protein 3 (Mitochondrial, Proton Carrier) (UCP3))
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别名
- UCP3
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背景
- Mitochondrial uncoupling protein 3 is a protein that in humans is encoded by the UCP3 gene. Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. The different UCPs have tissue-specific expression, this gene is primarily expressed in skeletal muscle. This gene's protein product is postulated to protect mitochondria against lipid-induced oxidative stress. Expression levels of this gene increase when fatty acid supplies to mitochondria exceed their oxidation capacity and the protein enables the export of fatty acids from mitochondria. UCPs contain the three solcar protein domains typically found in MACPs. Two splice variants have been found for this gene.
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UniProt
- P55916
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途径
- Proton Transport
抗原
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