Recombinant UFC1 抗体
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北京 101111
Quick Overview for Recombinant UFC1 抗体 (ABIN7882632)
抗原
See all UFC1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- UFC1 Antibody / Ubiquitin-fold modifier conjugating enzyme 1
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纯化方法
- Affinity-chromatography
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免疫原
- A synthesized peptide derived from human Ubiquitin-fold modifier conjugating enzyme 1 protein was used as the immunogen for the UFC1 antibody.
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亚型
- IgG
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anti-Ubiquitin-Fold Modifier Conjugating Enzyme 1 (UFC1) (C-Term) antibody
UFC1 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB6527 unconjugated
anti-Ubiquitin-Fold Modifier Conjugating Enzyme 1 (UFC1) antibodyUFC1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Fold Modifier Conjugating Enzyme 1 (UFC1) antibodyKD Validated UFC1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB4245 unconjugated Recombinant Antibody
anti-Ubiquitin-Fold Modifier Conjugating Enzyme 1 (UFC1) (AA 1-167) antibodyUFC1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ubiquitin-Fold Modifier Conjugating Enzyme 1 (UFC1) (AA 2-31), (N-Term) antibodyUFC1 适用: 人 WB 宿主: 兔 Polyclonal RB40483 unconjugated
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应用备注
- Optimal dilution of the UFC1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the UFC1 antibody at -20oC.
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- UFC1 (Ubiquitin-Fold Modifier Conjugating Enzyme 1 (UFC1))
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别名
- UFC1
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背景
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UFC1 antibody detects ubiquitin-fold modifier conjugating enzyme 1, an essential component of the UFM1 conjugation system. UFC1 functions as an E2-like enzyme that transfers UFM1 to substrate proteins, regulating diverse cellular processes such as ER homeostasis, stress responses, and protein quality control. The UFM1 pathway resembles ubiquitination but is distinct, making UFC1 a unique player in post-translational modification networks.
Research using UFC1 antibody has shown that defects in UFM1 conjugation can impair ER stress management and contribute to diseases including cancer and metabolic disorders. Variations in UFC1 function may alter cell survival and proliferation, and the pathway has been linked to hematopoietic development and cardiac physiology. Because UFMylation is less understood than ubiquitination, ongoing studies continue to reveal novel roles for UFC1 in cellular regulation.
Antibodies against UFC1 are validated for applications such as western blot, immunoprecipitation, and immunohistochemistry. These reagents allow researchers to track UFC1 expression levels and to explore its role in the transfer of UFM1 during cellular stress. Clone-specific performance provides consistency for labs investigating this unique modification pathway.
NSJ Bioreagents offers this UFC1 antibody to support research into UFMylation, protein quality control, and disease mechanisms. Alternate names include ubiquitin-fold modifier conjugating enzyme 1 antibody, UFM1-conjugating enzyme antibody, and UBC-E2 antibody. -
UniProt
- Q9Y3C8
抗原
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