TPT1 抗体
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北京 101111
Quick Overview for TPT1 抗体 (ABIN7882603)
抗原
See all TPT1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- TCTP Antibody / TPT1
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纯化方法
- Affinity purified
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免疫原
- A synthetic peptide specific to human TCTP / TPT1 was used as the immunogen for the TCTP antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the TCTP antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the TCTP antibody at -20oC.
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- TPT1 (Tumor Protein, Translationally-Controlled 1 (TPT1))
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别名
- TCTP
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背景
- The TPT1 gene encodes a protein that is a regulator of cellular growth and proliferation. Its mRNA is highly structured and contains an oligopyrimidine tract (5'-TOP) in its 5' untranslated region that functions to repress its translation under quiescent conditions. The encoded protein is involved in a variety of cellular pathways, including apoptosis, protein synthesis and cell division. It binds to and stabilizes microtubules, and removal of this protein through phosphorylation is required for progression through mitotic and meiotic cell divisions. This gene is known to play a role in carcinogenesis, and is upregulated in some cancer cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [RefSeq]
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UniProt
- P13693
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途径
- Response to Water Deprivation, Regulation of Cell Size, Negative Regulation of intrinsic apoptotic Signaling
抗原
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