Troponin I 抗体
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北京 101111
Quick Overview for Troponin I 抗体 (ABIN7882571)
抗原
See all Troponin I (TNNI) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Troponin I Antibody / TNNI3
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序列
- MMQALLGARA KESLDLRAHL KQ
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids MMQALLGARAKESLDLRAHLKQ were used as the immunogen for the Troponin I antibody.
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亚型
- IgG
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anti-Troponin I (TNNI) antibody
TNNI 适用: 人, 小鼠 WB, IHC 宿主: 小鼠 Monoclonal FI-23 unconjugated
anti-Troponin I (TNNI) (AA 1-50) antibodyTNNI 适用: 人, 小鼠 WB, IHC 宿主: 兔 Monoclonal BLR280L unconjugated Recombinant Antibody
anti-Troponin I (TNNI) antibodyTNNI 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 12F10 unconjugated
anti-Troponin I (TNNI) (pSer23), (pSer24) antibodyTNNI 适用: 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the Troponin I antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Troponin I antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Troponin I (TNNI)
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别名
- Troponin I
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背景
- Troponin I, cardiac muscle is a protein that in humans is encoded by the TNNI3 gene. Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). Troponin I is useful in making a diagnosis of heart failure, and of ischemic heart disease. An elevated level of troponin is also now used as indicator of acute myocardial injury in patients hospitalized with moderate/severe Coronavirus Disease 2019 (COVID-19). Such elevation has also been associated with higher risk of mortality in cardiovascular disease patients hospitalized due to COVID-19.
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UniProt
- P19429
抗原
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