Recombinant TIMM44 抗体
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Quick Overview for Recombinant TIMM44 抗体 (ABIN7882540)
抗原
See all TIMM44 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- TIMM44 Antibody / Translocase of inner mitochondrial membrane 44
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纯化方法
- Affinity-chromatography
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免疫原
- A synthesized peptide derived from human TIM44 was used as the immunogen for the TIMM44 antibody.
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亚型
- IgG
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anti-Translocase of Inner Mitochondrial Membrane 44 (TIMM44) (AA 1-452) antibody
TIMM44 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Translocase of Inner Mitochondrial Membrane 44 (TIMM44) (AA 153-452) antibodyTIMM44 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Translocase of Inner Mitochondrial Membrane 44 (TIMM44) (N-Term) antibodyTIMM44 适用: 人, 大鼠, 小鼠 WB, IF, ICC, IHC 宿主: 兔 Polyclonal unconjugated
anti-Translocase of Inner Mitochondrial Membrane 44 (TIMM44) antibodyTIMM44 适用: 人, 大鼠 WB, IF, ICC, IP, FACS 宿主: 兔 Monoclonal 30T70 unconjugated
anti-Translocase of Inner Mitochondrial Membrane 44 (TIMM44) (N-Term) antibodyTIMM44 适用: 人, 大鼠, 小鼠, 犬, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the TIMM44 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the TIMM44 antibody at -20oC.
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- TIMM44 (Translocase of Inner Mitochondrial Membrane 44 (TIMM44))
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别名
- TIMM44
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背景
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TIM44 antibody recognizes translocase of inner mitochondrial membrane 44, a central component of the mitochondrial protein import machinery. TIM44 anchors mitochondrial Hsp70 to the inner membrane, enabling preprotein translocation through the TIM23 complex. By facilitating proper protein targeting, TIM44 ensures mitochondrial biogenesis and maintenance of energy production.
Research using TIM44 antibody has highlighted its importance in mitochondrial function and human disease. Altered expression of TIM44 can impair protein import, leading to mitochondrial stress and metabolic dysfunction. Dysregulation has been linked to neurodegenerative conditions, where defective energy metabolism is a hallmark, and to metabolic syndromes associated with impaired mitochondrial quality control.
Validated clones for TIM44 detection are suitable for western blot, immunofluorescence, and immunohistochemistry. These reagents allow investigators to track mitochondrial protein import efficiency and examine changes in response to cellular stress. Monitoring TIM44 levels provides valuable insight into how cells adapt to demands on mitochondrial biogenesis and oxidative metabolism.
NSJ Bioreagents offers this TIM44 antibody to support studies in mitochondrial biology, metabolic regulation, and disease. Alternate names include translocase of inner mitochondrial membrane 44 antibody, mitochondrial import receptor subunit TIM44 antibody, and HSP-binding protein antibody. -
UniProt
- O43615
抗原
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