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Recombinant TSH receptor 抗体

This 兔 单克隆 antibody specifically detects TSH receptor in IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7882482
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant TSH receptor 抗体 (ABIN7882482)

抗原

See all TSH receptor (TSHR) 抗体
TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This TSH receptor antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

TSHRB-1607R
  • 原理

    Recombinant TSH Receptor Antibody / B-Chain

    纯化方法

    Protein A/G affinity

    免疫原

    Recombinant human TSHR B-Chain protein was used as the immunogen for the recombinant TSH Receptor antibody.

    亚型

    IgG, kappa
  • 应用备注

    Optimal dilution of the recombinant TSH Receptor antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the recombinant TSH Receptor antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))

    别名

    TSH Receptor

    背景

    Thyroid-stimulating hormone (TSH, also known as thyrotropin) is a glycoprotein involved in the control of thyroid structure and metabolism, which stimulates the release of the thyroid hormones. TSH is regulated by thyroid hormone (T3) and various retinoid compounds. TSH binds to the thyroid-stimulating hormone receptor (TSHR), which is cleaved into two subunits, A and B, and plays a major role in regulating thyroid function. The third cytoplasmic loop of TSHR has been identified as critical for its role in regulating inositol phosphate and cAMP formation. In Grave s disease, an autoimmune disorder, TSHR is activated by autoantibodies, which may be stimulated by the cleavage of the A and B subunits.

    UniProt

    P16473

    途径

    Thyroid Hormone Synthesis
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